Use of Nitrous Oxide in Dermatology: A Systematic Review

Brotzman, Erica; Sandoval, Laura F.; Crane, J.

doi:10.1097/dss.0000000000001464

Cited by 18 publications

(19 citation statements)

References 26 publications

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“…Intralesional anesthesia is beneficial for high energy ablative laser procedures to improve the patient experience. Patient‐controlled inhalation therapy with 50% oxygen and 50% nitrous oxide can be considered on a case‐by‐case basis for more extensive procedures .…”

Section: Discussionmentioning

confidence: 99%

Laser Therapy of Traumatic and Surgical Scars and an Algorithm for Their Treatment

et al. 2019

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Background and Objectives: This paper describes the laser techniques available for the treatment of surgical and trauma scars and develops recommendations for an algorithmic-based treatment approach based on extensive clinical experience and published data. Study Design/Materials and Methods: We reviewed the literature regarding laser treatment of surgical and traumatic scars and incorporated the clinical experience of the authors to develop an algorithm for the treatment of surgical and trauma scars. Results: In order to develop treatment recommendations, scars were differentiated based on their clinical characteristics. Specific scar characteristics aid in determining the appropriate treatment strategy for different types of complex surgical and trauma scars. Conclusion: Laser therapy is first-line therapy for traumatic and surgical scars. The treatment approach should be guided by scar characteristics (e.g., anatomic location, type of injury, color, thickness, tension, scar age, and activity) and involves choosing the appropriate laser type and determining the benefit of combination therapy with surgical and nonsurgical treatment modalities to optimize treatment responses. Lasers Surg. Med.

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Section: Discussionmentioning

confidence: 99%

Laser Therapy of Traumatic and Surgical Scars and an Algorithm for Their Treatment

et al. 2019

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“…It is therefore important not to assist the patient in holding or controlling the mouthpiece device. The use of nitrous oxide is well-established in dental literature and has been adopted to many dermatologic and aesthetic procedures, including tumescent liposuction, as a safe analgesic adjunct [26][27][28]. Additional monitoring with a pulse oximeter is advised for longer procedures.…”

Section: Nitrous Oxide (Pronox)mentioning

confidence: 99%

“…Adverse effects are mild and infrequent and include emotional lability (most commonly laughter and euphoria), nausea, and dizziness. It has a quick onset and recovery times are 5 to 10 minutes allowing for patients to drive themselves home following smaller local procedures [26].…”

Section: Nitrous Oxide (Pronox)mentioning

confidence: 99%

Enhanced Lipocontouring of the Arms

Khanna¹,

Saheb-Al-Zamani²

2022

Enhanced Liposuction - New Perspectives and Techniques

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The visibility of arm contour in both men and women has been a source of discussion throughout time. Arm strength and athleticism is not limited to the male physique only. Iconic women such as Madonna and Michelle Obama have made discussions about arm contour more and more commonplace. Over the years arm contour has been a difficult area to address due to the thinness of the skin which often required surgical excision and unsightly scars. Liposuction of the arm has advanced to not only allow for improved contour but also options of refining muscular definition. With the addition of energy-based technologies such as radiofrequency, we can offer less invasive options to patients who may have previously only been candidates for excisional procedures. Liposuction of the arms can be performed under local anesthesia. This chapter introduces a new algorithm for assessment and treatment of arm contour which incorporates newer energy-based devices along with surgical options.

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“…Originally largely localized to the field of dentistry, the gas has surged in popularity among medical specialties with outpatient procedures like dermatology, urology, and gastroenterology. [10][11][12] The recent ENIGMA II trial demonstrated the versatility and long-term safety of this agent 13 ; however, recent guidelines from an American Academy of Dermatology working group did not include N 2 O among its suggested adjuncts to local anesthetic injections in dermatologic surgery. 14 N 2 O is a tasteless gas with a slightly fruity odor.…”

Section: Nitrous Oxidementioning

confidence: 99%

Nitrous Oxide Reduces Pain Associated With Local Anesthetic Injections

2019

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Background Local anesthetic injections can be painful and distressing. Objective The aim of this study was to determine whether nitrous oxide, ice, vibration, or topical anesthetic improves analgesia for local anesthetic injections. Method A cohort study of 400 patients undergoing Mohs micrographic surgery with local anesthetic was conducted. Patients received no intervention ( n = 200), ice ( n = 50), topical anesthetic cream ( n = 50), vibration device ( n = 50), or nitrous oxide ( n = 50). Pain was rated using the Visual Analogue Scale (VAS) and Wong-Baker FACES Pain Rating Scale. Results Without intervention, mean VAS was 4.2 and FACES was 4.6. Nitrous oxide was the most successful in reducing pain (mean VAS 1.6 vs. 4.2, P < .01, FACES 1.2 vs. 4.6, P < .01). Topical ice reduced pain (mean VAS 3.0 vs. 4.2, P < .01, FACES 3.0 vs. 4.6, P < .01). Vibration reduced pain (mean VAS 3.5 vs. 4.2, P < .01, FACES 3.6 vs. 4.6, P < .01). Higher pain scores were associated with age <50 ( P = .02), male sex ( P = .05), and surgery on the nose, lip, ear, or eyelid ( P = .02). Conclusion Nitrous oxide, ice, and vibration reduce injection pain. These interventions are especially useful for younger males undergoing surgery on the nose, lip, ear, or eyelid.

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Use of Nitrous Oxide in Dermatology: A Systematic Review

Cited by 18 publications

References 26 publications

Laser Therapy of Traumatic and Surgical Scars and an Algorithm for Their Treatment

Laser Therapy of Traumatic and Surgical Scars and an Algorithm for Their Treatment

Enhanced Lipocontouring of the Arms

Nitrous Oxide Reduces Pain Associated With Local Anesthetic Injections

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