Use of medications with potential oral adverse drug reactions in community‐dwelling elderly

Abstract

Prevalence and indicators of medication use with potential oral health implications among 4,163 people from the Duke Established Populations for Epidemiologic Studies of the Elderly were studied. Medications were grouped into seven potential oral adverse drug reaction (POADR) categories. Eighty percent of participants were taking at least one medication from any of the seven categories. Drugs with the potential to cause xerostomia were taken by 56.1%, abnormal hemostasis by 51.7%, soft tissue reactions by 23.4%, taste changes by 11.0%, alteration in host resistance by 8.7%, gingival overgrowth by 5.0%, and movement disorders by 2.4% of participants. Race-stratified analyses revealed that medication use with any POADR was significantly associated (p < 0.001) with being female for both races. Among nonblacks, being > or = 75 years old was associated with higher POADR use. Blacks who had a dental visit in the previous six months were more likely to take medications with POADR than those who did not. POADR medication use was not related to place of residence. Elderly often take medications with potential oral health impact.

Exposure to the oral side effects of medication in a community-based sample

“…Table 2 displays the distribution of potential OSE according to our 16 main categories and compared them to the Iowa 65+ study' and the Piedmont study. 4 The distribution of subjects with respect to the number of potential OSE in five categories was: none, 20%; 1 to 2, 24%; 3 to 4,26%; 5 to 6, 14%; and 7 or more, 16% (Table 3 ) .…”

Avaliação sócio-odontológica de 300 pessoas idosas de Bauru - SP.

“…As condições médicas encontradas nos 300 idosos avaliados em 34,43,60,77 . Portanto os dentistas devem estar informados a respeito das doenças de seus pacientes bem como dos medicamentos por eles usados.…”

The effect of drugs on orthodontic tooth movement

“…To avoid undesirable influences on tooth movement, the orthodontist should be aware of any drugs taken by each individual patient. Moreover, when taken drugs are listed by the patient before the onset or during the course of orthodontic treatment, the orthodontist should explore and document their published effects and side effects (35). This information should enable the orthodontist to increase the precision of forecast of the treatment duration and outcome.…”