Use of an attenuated live Salmonella Typhimurium vaccine on three breeding pig units: A longitudinal observational field study

Maternal vaccination as aSalmonellaTyphimurium reduction strategy on pig farms

“…1,4,12:i‐) being frequently implicated (Andres and Davies ; Davies et al . ). Nonetheless, within the EU, there is no mandatory programme for the control of Salmonella at pork primary production level.…”

“…However, despite enhanced hygiene interventions at slaughter, the control of Salmonella carriage and shedding remains a challenge in most countries (Davies et al . ).…”

“…Several candidate vaccines for Salmonella in pigs have been developed, from inactivated bacterins to elicit a humoral response to live or adjuvanted vaccines that additionally stimulate cell‐mediated immunity (Davies et al . ). Live vaccines theoretically offer the best option, since they are able to stimulate cell‐mediated immunity (Mastroeni et al .…”

“…; Davies et al . ). Several studies have evaluated live vaccines for Salmonella Choleraesuis, a serovar that is particularly pathogenic to both pigs and some humans (Schwarz et al .…”

“…Longitudinal field studies examining natural infections are comparatively uncommon among reports of Salmonella vaccination trials in pigs (Davies et al . ). In this study, we developed a long‐term longitudinal field study to evaluate the efficacy of vaccination with an inactivated ST vaccine to all breeding sows present in the herd as a strategy to reduce the prevalence of Salmonella infection in farms with a salmonellosis problem.…”