Urolithiasis and obesity: metabolic and technical considerations

Calvert, Robert C.; Burgess, Neil

doi:10.1097/01.mou.0000160626.36236.22

Cited by 67 publications

(50 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Most lithotripters have a maximum skin to stone distance of 12-14 cm for their focal point and thus can restrict the acquired distance for complete stone fragmentation in obese patients [7,27] . Similar difficulties may also decrease the success rate of a percutaneous nephrolithotomy (PCNL) procedure in an obese patient with nephrolithiasis due to difficulties in percutaneous access, as well as limitations in the use of normal sized instruments and higher risk of anesthetic complications in prone position [7] .…”

Section: Management Of Obese Patients With Urolithiasismentioning

confidence: 99%

Urinary stone disease and obesity: Different pathologies sharing common biochemical mechanisms

Aydoğdu¹

2012

WJN

View full text Add to dashboard Cite

The prevalence of urolithiasis is increasing in parallel with the escalating rate of obesity worldwide. It has previously been speculated that obesity is a potential risk factor for urinary stone disease. The possibility that common biochemical mechanisms underlie both obesity and urolithiasis is remarkable. Better understanding of possible common mechanisms of these diseases could potentially lead to a better management of urinary stone prevention. The prevention of urinary stone formation gives clinicians an acceptable reason to encourage lifestyle modification and weight loss through a regular diet. In this review, the association of obesity with urinary stone disease, possible common biochemical mechanisms, effects of dietary habits and weight loss on stone formation, as well as difficulties in surgical management of obese individuals with urolithiasis are discussed.

show abstract

Section: Management Of Obese Patients With Urolithiasismentioning

confidence: 99%

Urinary stone disease and obesity: Different pathologies sharing common biochemical mechanisms

Aydoğdu¹

2012

WJN

View full text Add to dashboard Cite

show abstract

“…2,20 Obesity is also associated with metabolic derangements, which can increase the risk of urinary stone formation. 4,5 Since obese patients undergoing surgery pose a challenge to those caring for them, the impact of obesity on surgical complications has always been a topic of interest. 22 Choban et al reported that obesity was associated with an increase in the frequency and severity of complications in a wide variety of surgical procedures.…”

Section: Discussionmentioning

confidence: 99%

“…2 In addition, ample evidence exists that obesity is associated with metabolic derangements that may lead to the formation of urinary stones. [3][4][5] Obesity is defined by the quantity of adipose tissue rather than total body weight. 6 Recently, it has been recognized that abdominal adipose tissue is distributed into two main compartments with different anatomical and functional features: visceral abdominal adipose tissue and subcutaneous abdominal adipose tissue.…”

Section: Introductionmentioning

confidence: 99%

The effect of abdominal fat parameters on percutaneous nephrolithotomy success

Çakmak

Tarhan

Çimen

et al. 2016

CUAJ

View full text Add to dashboard Cite

Introduction: Obesity has been suggested to lower the success of percutaneous nephrolithotomy (PCNL). However, the relationship between abdominal fat parameters, such as visceral and subcutaneous abdominal adipose tissue, and PCNL success remained unclear. In this study, we aimed to investigate the effect of abdominal fat parameters on PCNL success. Methods: A total of 150 patients who underwent PCNL were retrospectively enrolled in this study. Group 1 consisted of patients who had no residual stones or residual stone fragments <3 mm in diameter while group 2 included patients with residual stone fragments ≥3 mm. PCNL procedure was defined as successful if all stones were eliminated or if there were residual stone fragments <3 mm in diameter confirmed by non-contrast computed tomography (NCCT) performed postoperatively. Preoperative NCCT was used to determine abdominal fat parameters. Results: Group 1 consisted of 117 (78.0%) patients while group 2 included 33 (22.0%) patients. On univariate analysis, stone number, stone surface area (SSA), visceral fat area (VFA), abdominal circumference on computerized tomography (ACCT), and duration of procedure were found to be predictive factors affecting PCNL success. Logistic regression analysis revealed that ACCT and SSA were independent prognostic factors for PCNL success. Conclusions: PCNL success was not affected by VFA, subcutaneous fat area (SFA) and body mass index (BMI) in our series. However, ACCT and SSA had negative associations with PCNL success. We conclude that both ACCT and SSA can be used as tools for predicting PCNL outcomes.

show abstract

“…In these obese patients, a frequent factor limiting the success of ESWL is positioning the patient so the stone can be located at the focal point of the lithotripter. Most lithotripters have a maximum skin to stone distance of 12-14 cm for their focal point, which can restrict the depth in which stone fragmentation can be accomplished (9). For this reason, ESWL for obese patients may be a sub-optimal treatment.…”

Section: ) According To the World Health Organizationmentioning

confidence: 99%

Impact of obesity on ureteroscopic laser lithotripsy of urinary tract calculi

et al. 2009

View full text Add to dashboard Cite

Purpose: The treatment of urinary tract stones in obese patients may differ from the treatment of non-obese patients and their success rate varies. Our objective was to compare ureteroscopic treatment outcomes of ureteral and renal stones, stratified for stone size and location, between overweight, obese and non-obese patients. Materials and Methods: Charts were reviewed for 500 consecutive patients presenting at our institution for renal and ureteral stones. A total of 107 patients underwent flexible or semi-rigid ureteroscopy with Ho:YAG laser lithotripsy and met criteria for review and analysis. Results: Overall, initial stone-free rates were 91%, 97%, and 94% in normal, overweight and obese individuals respectively. When compared to non-obese patients, there were no significant differences (p value = 0.26; 0.50). For renal and proximal ureteral stones, the stone-free rate in overweight and obese individuals was 94% in both groups; and a stone-free rate of 100% was found for distal stones, also in both groups. Conclusions: Ureteroscopic treatment of stones in obese and overweight patients is an acceptable treatment modality, with success rates similar to non-obese patients.

show abstract

Urolithiasis and obesity: metabolic and technical considerations

Abstract: Urolithiasis can be safely and effectively managed in obese patients with minor modifications to the established surgical techniques. Increased understanding of the underlying metabolic abnormalities in obese patients with urolithiasis may improve prevention strategies in the future.

Cited by 67 publications

References 36 publications

Urinary stone disease and obesity: Different pathologies sharing common biochemical mechanisms

Urinary stone disease and obesity: Different pathologies sharing common biochemical mechanisms

The effect of abdominal fat parameters on percutaneous nephrolithotomy success

Impact of obesity on ureteroscopic laser lithotripsy of urinary tract calculi

Contact Info

Product

Resources

About