Urea assisted hydroxyapatite mineralization on MWCNT/CHI scaffolds

Advances in Biomimetic and Nanostructured Biohybrid Materials

“…9). [109] Alternatively, CNT-based scaffolds prepared by nanosphere lithography using polystyrene templates show an elevated Young's modulus together with biocompatibility for the growth of human osteoblast cells. [110] Another advantage in the use of CNTs for scaffold applications has been shown by Voge et al, who report the combination of SWNTs with a collagen-fibrin matrix.…”

Preparation of aligned porous gelatin scaffolds by unidirectional freeze-drying method

“…In addition, this method was also used to prepare unidirectional porous carbon nanotube or poly (L-lactic acid) scaffolds [29,30], as well as free-standing all-nanoparticle thin fibers [31,32]. The biocompatibility of the scaffold was improved by modification of the scaffold with natural polymers and natural particles such as HAP [33].…”

Progress in Bionanocomposite and Bioinspired Foams

“…[ 16 ] More recently, we have demostrated that, besides collagen expressing cells, the incorporation of HA precursors (Figure 2 c) can also contribute to bone tissue regeneration. [ 17 ] Besides the use of scaffolds as tridimensional substrates for tissue engineering purposes, the design of hierarchical foams for drug delivery and controlled release is particularly interesting as well, considering that the release of crystalline needles of ciprofl oxacin (CFX, an antibiotic which primary mechanism of action against microorganisms involves inhibition of topoisomerase IV and DNA gyrase) entrapped within polymeric scaffolds can be controlled by either the macroporous structure of the scaffold [ 18 ] or the peculiarities of the CFX polymorph that can be eventually obtained upon enzymatically induced precipitation. [ 19 ] The hierarchical porosity of these foams together with the functionality afforded by the polymer can also be used for removal of pollutants or harmful compounds.…”