Unusual Primary Ocular Manifestation of Sarcoidosis

Deuchler, Svenja; Wagner, Clemens; Schill, Markus A.; Schöne, Benjamin; Scherer, Daniel; Singh, Pankaj; Kohnen, Thomas; Koch, Frank

doi:10.1159/000501302

Cited by 5 publications

(4 citation statements)

References 15 publications

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“…The lacrimal gland is reported to be affected in 15.8% of ocular sarcoidosis [17]. The diagnosis of lacrimal gland involvement is based on clinically enlarged gland, presence of dry eye and microscopic presence of chronic non-caseating granulomatous inflammation of the nasolacrimal duct mucosa [7,17]. Our case of isolated orbital sarcoidosis presented with left inner canthus swelling, without any systemic disease.…”

Section: Discussionmentioning

confidence: 75%

“…Cutaneous sarcoidosis of the eyelids presents in the form of millet-seed nodular lesions [16]. The lacrimal gland is reported to be affected in 15.8% of ocular sarcoidosis [17]. The diagnosis of lacrimal gland involvement is based on clinically enlarged gland, presence of dry eye and microscopic presence of chronic non-caseating granulomatous inflammation of the nasolacrimal duct mucosa [7,17].…”

Section: Discussionmentioning

confidence: 99%

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A Rare Presentation of Solitary Ocular Sarcoidosis

Mohamad¹,

Rahman²,

Haiyat³

et al. 2021

JCHS

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Ocular sarcoidosis leads to inflammation of the eye, manifesting as uveitis, scleritis and conjunctivitis with granuloma formation. It can involve any part of the eye and its adnexal tissues, and may result in complications like glaucoma and cataract. Ophthalmic manifestations of sarcoidosis can be isolated, or it may be associated with other organs of the body. The clinical presentation in ocular sarcoidosis is quite varied. Multi-disciplinary modality of treatment is required for both ocular and systemic manifestations of the disease. We report a rare presentation of solitary ocular sarcoidosis in a 42-year-old woman, who presented with complaints of painless left inner canthus swelling and blurry vision for 1 month.

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Section: Discussionmentioning

confidence: 75%

Section: Discussionmentioning

confidence: 99%

A Rare Presentation of Solitary Ocular Sarcoidosis

Mohamad¹,

Rahman²,

Haiyat³

et al. 2021

JCHS

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“…Not much international data is available on treatment options in sarcoidosis. Deuchler stated a case report with the lone use of steroid in a patient with complete recovery 19 . Certain studies worked in identification of ocular sarcoidosis appear to be a useful decisive clinical marker for determining the prognostic outcome of sarcoidosis patients 20 .…”

Section: Discussionmentioning

confidence: 99%

Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan.

Ishaq,

Riaz,

Iqbal

et al. 2024

ashkmdc

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Objectives: The Primary objective was to find the frequency of Sarcoid Uveitis among the patients pre- sented with Uveitis.The secondary objective was to follow the patients of sarcoid uveitis over treat- ment.. Methods: We did an observational prospective study, after acquiring ethical review letter from IRB Medicine department outpatient services of Jinnah Medical College Hospital Korangi was used where patients with Uveitis were referred for evaluation of systemic disease during jan 2019 to dec 2020. These patients underwent history, examination and biochemical and radiological investigations and were followed over a period of 1 year to see response to treatment. Results: A total of 372 patients presented with established uveitis out of which 36 patients i.e. 66 eyes presented to our eye clinic with decrease in vision with a mean age of 42±2 years. Among 36 patients, 89% presented with redness of eye and 72% presented with eye pain where as 8 % pre- sented with photophobia and floaters. Biochemically >10mg/dl calcium was observed in 18(50%) pa- tients and ACE level was found to be more than 40nmol/ml/min in 30(83.3%) patients. Among them 32 (88.9%) patients showed resolved inflammation whereas 2(5.56%) showed a change in inflamma- tion and 2(5.56%) showed no change. Conclusion: We found sarcoid uveitis as fairly common cause of uveitis. The patients were treated with the standard treatment of steroids and immunosuppressants i.e. Azathioprine and we concluded that use of steroids and immunosuppressant improved the outcome in our patients. The patients re- sponded fairly well to the designed treatment.

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“…Currently, there is a reported collection of symptoms that have been noted as NS. These symptoms range from blurry vision and floaters to a skin tattoo reaction [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

A 46-Year-Old Presenting With Inferior Mononuclear Visual Field Defect as the Sole Manifestation of Neurosarcoidosis

Hoegerl¹,

Amper²

2021

Cureus

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Neurosarcoidosis (NS) is a rare manifestation of sarcoidosis that lacks an organized body of knowledge regarding its diagnosis and management. There exists no clearly defined diagnostic criteria to make the diagnosis. To further complicate things, biopsy of the nervous system tissue remains complicated and not easily accomplished due to the sensitivity of the tissue and the subsequent deficits it could produce. In this case report, we present a patient who presented with acute inferior mononuclear quadrantanopsia with an insignificant past medical history and a lack of other signs and symptoms. Follow-up studies and magnetic resonance imaging of the orbits eventually led to the diagnosis of NS.

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Unusual Primary Ocular Manifestation of Sarcoidosis

Cited by 5 publications

References 15 publications

A Rare Presentation of Solitary Ocular Sarcoidosis

A Rare Presentation of Solitary Ocular Sarcoidosis

Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan.

A 46-Year-Old Presenting With Inferior Mononuclear Visual Field Defect as the Sole Manifestation of Neurosarcoidosis

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