Unusual Forms of Adrenal and Extra-Adrenal Myelolipomas

Suárez-Peñaranda, José Manuel; Naveira, Alberto; Fraga, Máximo; Aliste-Santos, Carlos; Cordeiro, Cristina Robalo; Barús, José Ignacio Muñoz

doi:10.1177/1066896914521289

Cited by 11 publications

(5 citation statements)

References 9 publications

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“…Others suggest that a preoperative biopsy should be considered, as the pathologic results have the ability to strongly impact management, particularly for lesions that are large or invade adjacent structures. 11 Concurrent presentation of myelolipomas with other neoplasms (adrenal adenoma, focal nodular hyperplasia, non-Hodgkin lymphoma) are reported in literature. 12 An incidental finding in our patient was 2 spindle cell tumors on the gastric surface.…”

Section: Discussion and Review Of Literaturementioning

confidence: 99%

Giant Extra-Adrenal Retroperitoneal Myelolipoma With Incidental Gastric Mesenchymal Neoplasias

Yildiz

2015

International Surgery

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Extra-adrenal myelolipomas are rare, benign tumors composed of adipose tissue and hematopoietic cells. Almost all myelolipomas occur within the adrenal gland. Only 50 cases of myelolipomas were described in literature and none of these were associated with gastric mesenchymal neoplasia. A 72-year-old male patient presented to a family medicine outpatient clinic with dyspnea and urinary urgency. His abdominal sonography revealed a 9-cm intra-abdominal mass. An incidental finding was 2 separate masses 1 cm each on the serosal surface of the stomach. The pathology specimen of the retroperitoneal mass revealed myelolipoma histopathology while gastric masses were reported as spindle cell mesenchymal neoplasias. The association of gastric spindle cell tumor and myelolipoma was not reported before in medical literature. Extra-adrenal myelolipomas are rare lesions, but should be considered in the differential diagnosis of fat containing retroperitoneal masses that are well circumscribed.

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Section: Discussion and Review Of Literaturementioning

confidence: 99%

Giant Extra-Adrenal Retroperitoneal Myelolipoma With Incidental Gastric Mesenchymal Neoplasias

Yildiz

2015

International Surgery

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“…They may coexist with hormone-secreting adrenal masses, but AMLs are always hormonally inactive [2]. Theories about their pathogenesis include reticuloendothelial cell metaplasia of adrenal capillaries, emboli from bone marrow and adrenal embryonic remnants of hematopoietic elements, while there is a report of myelolipoma expressing (3;21) (q25;p11) translocation which indicates a neoplastic process of hematologic origin [5].…”

Section: Discussionmentioning

confidence: 99%

Macroscopic Appearance of Giant Adrenal Myelolipoma During Laparoscopy: An Adjunct in Differential Diagnosis

Katsimantas¹,

Filippou

Melloy

et al. 2020

Cureus

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Giant adrenal myelolipoma is a rare, benign, sizable, mesenchymal tumor. Preoperative differential diagnosis from retroperitoneal liposarcoma may be challenging. A 66-year-old female patient was admitted because of a sizable tumor at the right retroperitoneal space, incidentally discovered during abdominal ultrasonography for screening purpose. Preoperative imaging studies were indicative for the diagnosis of a giant adrenal myelolipoma (11.7 × 12.9 cm in size); however, a retroperitoneal liposarcoma could not be excluded. We decided to proceed with tumor's surgical removal by using laparoscopic transperitoneal approach and threedimensional high-definition camera. Intraoperatively, the tumor did not infiltrate surrounding tissues and was surrounded by a thin capsule under which there were sparse, orange-colored spots that resembled adrenal cortex. This finding reinforced the initial and most possible diagnosis of adrenal myelolipoma and we easily enucleated the mass. Postoperative course was uneventful, and the patient demonstrated no recurrence on imaging six months postoperatively. Histology confirmed the diagnosis of giant adrenal myelolipoma, measuring 16.5 x 15 x 6.5 cm.

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“…Muchos cirujanos consideran que la biopsia es una contraindicación en cualquier lesión que sea resecable, debido a los riesgos de siembra en el tracto de la aguja de biopsia con células potencialmente malignas, o de infectar la lesión. Otros sugieren que se debe considerar una biopsia preoperatoria, ya que los resultados patológicos intervienen en el manejo, particularmente para las lesiones que son grandes o que invaden las estructuras adyacentes 8 . No existe un tratamiento estándar para este tipo de tumores.…”

Section: Discussionunclassified

Mielolipoma retroperitoneal perirrenal: reporte de un caso

Andrada¹,

Signorini²,

Alcaraz³

et al. 2020

CIRU

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El mielolipoma es un tumor benigno de baja incidencia cuya localización más frecuente son las glándulas suprarrenales. Histológicamente se caracteriza por células con precursores mieloides y eritroides mezcladas con tejido adiposo maduro. El diagnóstico en general es incidental en una prueba de imagen. Clínicamente cursa asintomático, aunque los de mayor tamaño tienen más riesgo de complicaciones como sangrado o efecto de masa. Los hallazgos incidentales < 4 cm se deben controlar con imágenes; los > 7 cm, o que generen síntomas, deben ser tratados de forma quirúrgica. Se reporta un caso de mielolipoma extrasuprarrenal en un paciente de 78 años.

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Unusual Forms of Adrenal and Extra-Adrenal Myelolipomas

Cited by 11 publications

References 9 publications

Giant Extra-Adrenal Retroperitoneal Myelolipoma With Incidental Gastric Mesenchymal Neoplasias

Giant Extra-Adrenal Retroperitoneal Myelolipoma With Incidental Gastric Mesenchymal Neoplasias

Macroscopic Appearance of Giant Adrenal Myelolipoma During Laparoscopy: An Adjunct in Differential Diagnosis

Mielolipoma retroperitoneal perirrenal: reporte de un caso

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