Unusual 6'-fatty acid esters of (24S)-24-ethylcholesta-5,25-dien-3β-yl β-d-glucopyranoside from Teucrium fruticans

Fontana, Gianfranco; Savona, Giuseppe; Rodrı́guez, Benjamı́n; Torre, Marı́a C. de la

doi:10.1016/s0031-9422(98)00511-1

Cited by 15 publications

(12 citation statements)

References 14 publications

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“…Phytochemical investigations on Teucrium spp. have shown the presence of compounds such as diterpene derivatives (Mini et al, 1991), fatty acid esters (Fonta et al, 1999), flavonoids (Rizk et al, 1986) and steroids (Ulubelen et al, 1994). However, so far, the biological activity of these compounds with respect to the hypoglycaemic effect of the plant has not been reported.…”

Section: Discussionmentioning

confidence: 99%

Hypoglycaemic effect of Teucrium polium: studies with rat pancreatic islets

Esmaeili

Yazdanparast

2004

Journal of Ethnopharmacology

157

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Section: Discussionmentioning

confidence: 99%

Hypoglycaemic effect of Teucrium polium: studies with rat pancreatic islets

Esmaeili

Yazdanparast

2004

Journal of Ethnopharmacology

157

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“…Sitosterol and clerosterol were detected in T. chamaedrys (Gaspar et al, 1996). Fontana et al (1999) reported also the isolation of 6′-fatty acid esters of (24S)-24-ethylcholesta-5,25-dien-3-yl-glucopyranoside from T. fruticans. GC analyses of the sterol isolated from T. polium, T. nabli, and T. alopecurus seed oil showed the presence of four Δ5 sterols (campesterol, stigmasterol, clerosterol, sitosterol), wherein the sterol marker was clerosterol, which comprised 44.3, 47, and 58.9%, respectively in T. nabli, T. polium, and T. alopecurus of the total sterol content, followed by stigmasterol and sitosterol, which percentages are different according to the species (Hachicha et al, 2009).…”

Section: Phytosterols and Tocopherolsmentioning

confidence: 92%

Medicinal halophytes: potent source of health promoting biomolecules with medical, nutraceutical and food applications

Ksouri

Megdiche-Ksouri

Jallali

et al. 2011

Critical Reviews in Biotechnology

349

261

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Salt-tolerant plants grow in a wide variety of saline habitats, from coastal regions, salt marshes and mudflats to inland deserts, salt flats and steppes. Halophytes living in these extreme environments have to deal with frequent changes in salinity level. This can be done by developing adaptive responses including the synthesis of several bioactive molecules. Consequently, several salt marsh plants have traditionally been used for medical, nutritional, and even artisanal purposes. Currently, an increasing interest is granted to these species because of their high content in bioactive compounds (primary and secondary metabolites) such as polyunsaturated fatty acids, carotenoids, vitamins, sterols, essential oils (terpenes), polysaccharides, glycosides, and phenolic compounds. These bioactive substances display potent antioxidant, antimicrobial, anti-inflammatory, and anti-tumoral activities, and therefore represent key-compounds in preventing various diseases (e.g. cancer, chronic inflammation, atherosclerosis and cardiovascular disorder) and ageing processes. The ongoing research will lead to the utilisation of halophytes as a new source of healthy products as functional foods, nutraceuticals or active principles in several industries. This contribution focuses on the ethnopharmacological uses of halophytes in traditional medicine and reviews recent investigations on their biological activities and nutraceuticals. The work is distributed according to the different families of nutraceuticals (lipids, vitamins, proteins, glycosides, phenolic compounds, etc.) discussing the analytical techniques employed for their determination. Information about the claimed health promoting effects of the different families of nutraceuticals is also provided together with data on their application.

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“…Indeed, the genus Teucrium has been reported as one of the richest sources of such products (Savona et al 1978;Bruno et al 1999;Coll and Tandrón 2004). Studies of T. fruticanshave resulted in the identification and isolation of other metabolites, including flavonoids that have diverse beneficial biochemical and antioxidant effects (Kisiel et al 2001), fatty acid esters (Fontana et al 1999), and important essential oils such as ß-myrcene, an important chemical used in the perfumery industry (Flamini et al 2001). …”

Section: Introductionmentioning

confidence: 99%

Micropropagation of Teucrium fruticans L., an ornamental and medicinal plant

Frabetti

Gutiérrez-Pesce

Gyves

et al. 2009

In Vitro Cell.Dev.Biol.-Plant

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An efficient protocol for in vitro propagation of the valuable ornamental and medicinal plant Bush germander (Teucrium fruticans L.) was developed through axillary shoot proliferation. A Murashige and Skoog agar medium supplemented with benzylaminopurine (6.6 μM), α-naphthaleneacetic acid (0.053 μM), and sucrose (3%) significantly improved the production of multiple shoots directly from nodal segment explants, resulting in an average of 2.8 shoots per segment with an average of 6.8 nodes per shoot that would be potential newly formed explants. The new shoots were developed without a marked decrease in the average height of the shoots. Shoots treated with 2.5 μM indole-3-butyric acid showed the highest average root number (7.9) and the highest percentage of rooting (94%). Plantlets were hardened off and transferred to jiffy pots for acclimatization under greenhouse conditions, resulting in a 100% survival rate.

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Unusual 6'-fatty acid esters of (24S)-24-ethylcholesta-5,25-dien-3β-yl β-d-glucopyranoside from Teucrium fruticans

Cited by 15 publications

References 14 publications

Hypoglycaemic effect of Teucrium polium: studies with rat pancreatic islets

Hypoglycaemic effect of Teucrium polium: studies with rat pancreatic islets

Medicinal halophytes: potent source of health promoting biomolecules with medical, nutraceutical and food applications

Micropropagation of Teucrium fruticans L., an ornamental and medicinal plant

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