Untersuchungen �ber die Aktivit�t der Adenosin-Desaminase im Plasma bei Krebskrankheiten unter besonderer Ber�cksichtigung des Bronchialcarcinoms

Letnansky, K.; Seelich, F.

doi:10.1007/bf01481952

Cited by 11 publications

(3 citation statements)

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“…As Letnansky and Seelich [9] have demonstrated, the values obtained with this method are similar to those obtained with the method of Conway and Cooke [1] in which adenosine deaminase activity in blood plasma or serum is estimated by determining ammonia levels in a buffered mixture before and after deamination of adenosine to inosine.…”

Section: Methodssupporting

confidence: 64%

Adenosine Deaminase Activity in Liver Diseases

Gc¹,

Rezzonico²,

Gervasini³

1967

Enzymol Biol Clin

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Serum adenosine deaminase levels were studied in normal subjects and in patients with liver diseases. A raised activity was observed in patients with viral hepatitis and with early cirrhosis of the liver. A smaller increase was demonstrated in patients with advanced cirrhosis of the liver. No increase in serum adenosine deaminase activity was detected in patients with hepatic coma. The decrease in serum adenosine deaminase activity in the course of cirrhosis from early stage to terminal coma is statistically significant. This decrease is correlated with increasing ammonia levels : the results suggest that increased blood ammonia levels may inhibit serum adenosine deaminase activity.

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Section: Methodssupporting

confidence: 64%

Adenosine Deaminase Activity in Liver Diseases

Gc¹,

Rezzonico²,

Gervasini³

1967

Enzymol Biol Clin

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“…The serum levels of IgG, IgA and IgM were normal. For the gene marker studies, the activity of adenosine deaminase of the patient's red blood cells was measured by the modified method of Letnansky and Seelich (1958). The average and standard deviation of the enzyme activity of 15 samples from early childhoods was 68.4_+6.6 moles adenosine/g Hb/hr and the enzyme activity of the patient was 78.0 moles adenosine/g Hb/hr which was determined to be within normal range.…”

Section: Case Reportmentioning

confidence: 99%

A partial short arm deletion of chromosome 20∶46, XY, del(20)(p11)

et al. 1978

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SummaryWe have. id.entified a partial deletiotl of the 8hart arm of chromosome 20 in a .5-ye.0r~-o!d boy from pareu.t~ having norm~! phenotype and ka~otype, Hi~ major anomalies were mild .mer~tal retardation, eongenita! be.art di~sease., chest deformity, s~pina bifido, kyphosco!io~is, inguinal hernia, and preaurjcula.r fistula, Th# c.lin, ic0! findings were tompared with those of two patLe0t~ r~eport~d pre~viou_s!y o~ a partial deletion 20p.T~ activity of adeno.sine deamin.ase in the patJent'~ red blood r162 was within normal range, sugge~sting that the gene. locus for the enzyme, which has been pr~evioosly as_signr to ~hromosom~ 20, may not pre.sent on pl !--*pter of chromosome 20,

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“…16, 21], In human blood ADA has been described in erythrocytes [7], leukocytes [14], platelets [10. 11] and in serum or plasma [13,15].…”

Section: Introductionmentioning

confidence: 99%