Understanding the association between dietary antioxidants, redox status and disease: is the Total Antioxidant Capacity the right tool?

Abstract

Total Antioxidant Capacity (TAC) considers the cumulative action of all the antioxidants present in plasma and body fluids, thus providing an integrated parameter rather than the simple sum of measurable antioxidants. The capacity of known and unknown antioxidants and their synergistic interaction is, therefore, assessed, thus giving an insight into the delicate balance in vivo between oxidants and antioxidants. There is new evidence indicating the importance of understanding the mechanisms of the homeostatic control of TAC in plasma and tissues and its modification during oxidative stress development. Recently, the epidemiological application of TAC has been proposed as a new tool for investigating the relationship between dietary antioxidants and cancer risk in population studies. This review outlines the pros and cons of the more common assays for measuring plasma TAC and the latest findings on dietary modulation of plasma redox status. Finally, the feasibility of the 'TAC concept' as an innovative tool for investigating the association between diet and oxidative stress is discussed.

Antioxidant property of synbiotic combination of Lactobacillus sp. and wheat bran xylo-oligosaccharides

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A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain

“…With this approach the capacity of both known and unknown antioxidants and their synergistic interaction is, therefore, included, and provides a better insight into the delicate in vivo balance between cellular oxidants and antioxidants (Serafini and Del Rio, 2004).…”

The Effects Caused by Lavender and Rosemary for Salivary Cortisol, Stress Levels and Mood Alteration

“…On the contrary, rosemary is rich in oxides and monoterpene which stimulate nervous system under the control of the parasympathetic nervous system, enhancing memory and concentration (Serafinim & Rio, 2004 In spite of the facts that there were some limitations that the number of the subjects was too small and the subjects were all females, it was possible to confirm that the aromatherapy alleviated stress levels without much inconvenience to the subjects. As a researcher, .…”