“…In this study, heterogeneity was present and the meta-regression analysis indicated that none of the selected variables (year of study, hospitalization sector, sample size and methodological quality) contributed as a source of heterogeneity to the analyses. However, it may be associated with differences between the studies, such as the health systems and institutions of the countries, given the peculiarities of health systems around the world, the characteristics of the institutions, the level of technology (Silva da & Elias, 2019;Souza, 2020) the establishment of clinical protocols for the preparation and administration of medicines, the sizing of nursing staff, working conditions, the dynamics of the services, among others (ASHP, 2018;WHO, 2017).…”