Ultrasonic promoted synthesis of 1,6-naphthyridine derivatives catalyzed by solid acid in water

Li, Chunmei; Qi, Chenze; Zhang, Furen

doi:10.1016/j.tetlet.2020.152144

Cited by 10 publications

(3 citation statements)

References 33 publications

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“…The same research team extended this protocol with slight modifications, replaced acetic acid with solid acid (C-SO3H), 1,3-cyclohexandione instead of Meldrum's acid. [42] The yields obtained through this protocol are similar to the previous method. Replacing the aromatic aldehyde with isatin is well tolerated.…”

Section: From 4-aminopyridine Derivativesupporting

confidence: 61%

Synthesis of 1,6‐Naphthyridine and Its Derivatives: A Systematic Review

2021

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The naturally and synthetically obtained 1,6-naphthyridine derivatives possess a wide range of pharmacological properties. This factor inspired the medicinal chemists and organic chemists to develop new methods for the synthesis of 1,6-naphthyridine derivatives. This review will discuss the synthesis of 1,6-naphthyridine and its derivatives from diverse starting materials or key intermediates in a systematic manner with appropriate mechanisms.

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Section: From 4-aminopyridine Derivativesupporting

confidence: 61%

Synthesis of 1,6‐Naphthyridine and Its Derivatives: A Systematic Review

2021

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“…Therefore, design simple synthetic route for synthesis of 1,6-naphthyridines is necessary demand for chemists. [63][64][65] Li et al [66] have reported an efficient and highly eco-friendly water mediated practical approach under ultrasound irradiations for synthesis of poly-substituted 1,6-naphthyridine derivatives 53 in 69-89 % yield via aqueous mediated three component reaction of 4-aminopyridinone 52, 1,3-cyclohexanedione/cylohexanone 14 and aromatic aldehydes 4 under sonication using solid acid (C-SO 3 H) as catalyst synthesized from hydrothermal carbonization of furaldehyde and hydroxyethylsulfonic acid.…”

Section: Synthesis Of 16-naphthyridine Derivativesmentioning

confidence: 99%

SO₃H‐Functionalized Carbon Materials: A Versatile and sustainable heterogeneous Catalyst for Diverse Organic Transformations

Singh,

Yadav,

Bhardwaj

et al. 2023

ChemistrySelect

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Due to their fascinating biological features, heterocyclic compounds and their derivatives have long been recognized as promising molecules with potential pharmaceutical applications. The significance of heterocyclic compounds in drug discovery and development is evident from the fact that a majority of drugs in the pharmaceutical market incorporate heterocyclic compounds as active substances or ingredients. Various synthetic methods and advancements have been devised to prepare these heterocyclic compounds using diverse catalysts under mild reaction conditions. SO3H functionalized carbon material (C‐SO3H) is heterogeneous green solid catalyst that has been employed to catalyze diverse organic reactions including construction of three‐, four‐, five‐, six‐member and fused heterocycles as well as other open chain organic transformations. The C‐SO3H catalyst works under relatively mild reaction conditions and recovered from the reaction mixtures for reuse. Various cheap carbon sources covering natural organic carbon matter and industrial waste already being used to synthesize SO3H‐functionalized acidic carbon catalyst for replacement of various homogeneous acid catalysts. The present review aims to highlight the organic reactions especially those connecting for heterocyclic synthesis catalyzed by sulfonated carbons (C‐SO3H) from 2010 to till date.

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“…Solid acid carbonaceous materials (C-SO 3 H) have emerged as heterogeneous catalysts of interest in greener organic synthesis, due to the fact that they combine acid catalytic properties with the possibility of more efficient recycling. In this perspective, Li et al [182] have reported a viable protocol for the synthesis of 1,6-naphthyridine derivatives ( 83 and 84 ) using this type of material via one-pot condensation of 4-aminopyridinones ( 82 ), aromatic aldehyde ( 1 ) or isatin ( 64 ), and dimedone ( 4 ), in aqueous media ( Scheme 31 ). The reaction was performed in an ultrasonic cleaner (40 kHz frequency, 200 W nominal power) at 60 °C and the temperature of the water bath was controlled at given temperature.…”

Section: Ultrasound-assisted Mcrs Under Heterogeneous Catalysismentioning

confidence: 99%

Greener organic synthetic methods: Sonochemistry and heterogeneous catalysis promoted multicomponent reactions

Machado

Santos

Januario

et al. 2021

Ultrasonics Sonochemistry

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Ultrasonic promoted synthesis of 1,6-naphthyridine derivatives catalyzed by solid acid in water

Cited by 10 publications

References 33 publications

Synthesis of 1,6‐Naphthyridine and Its Derivatives: A Systematic Review

Synthesis of 1,6‐Naphthyridine and Its Derivatives: A Systematic Review

SO₃H‐Functionalized Carbon Materials: A Versatile and sustainable heterogeneous Catalyst for Diverse Organic Transformations

Greener organic synthetic methods: Sonochemistry and heterogeneous catalysis promoted multicomponent reactions

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Ultrasonic promoted synthesis of 1,6-naphthyridine derivatives catalyzed by solid acid in water

Cited by 10 publications

References 33 publications

Synthesis of 1,6‐Naphthyridine and Its Derivatives: A Systematic Review

Synthesis of 1,6‐Naphthyridine and Its Derivatives: A Systematic Review

SO3H‐Functionalized Carbon Materials: A Versatile and sustainable heterogeneous Catalyst for Diverse Organic Transformations

Greener organic synthetic methods: Sonochemistry and heterogeneous catalysis promoted multicomponent reactions

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Product

Resources

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SO₃H‐Functionalized Carbon Materials: A Versatile and sustainable heterogeneous Catalyst for Diverse Organic Transformations