Greener organic synthetic methods: Sonochemistry and heterogeneous catalysis promoted multicomponent reactions

Machado, Ingrid V.; Santos, Jhonathan Renner Nunes dos; Januario, Marcelo A.P.; Corrêa, Arlene G.

doi:10.1016/j.ultsonch.2021.105704

Cited by 45 publications

(13 citation statements)

References 245 publications

(336 reference statements)

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“…Ultrasonication can promote the dispersion of magnetic nanoparticles (MNPs) in reaction mixtures, leading to a larger active surface area that can catalyze reactions. [ 101 ]…”

Section: Categories Of Mechanochemistrymentioning

confidence: 99%

“…Ultrasonication can promote the dispersion of magnetic nanoparticles (MNPs) in reaction mixtures, leading to a larger active surface area that can catalyze reactions. [101] Compared with other mechanochemical techniques, ultrasonic mechanochemistry is only suitable for liquid phase reactions. [91] Copyright 2020, The Authors, published by MDPI.…”

Section: Ultrasonication-induced Mechanochemistrymentioning

confidence: 99%

See 1 more Smart Citation

A Review on Mechanochemistry: Approaching Advanced Energy Materials with Greener Force

Liu

Zeng

et al. 2022

Advanced Materials

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high volatility, and poor security, renewable energy must be converted and stored before it can be stably and efficiently used. [2] Energy conversion refers to the conversion of one form of energy to another form, or several forms. This is achieved through energy conversion devices and corresponding technologies. The core part of energy conversion devices is the active material, which is also the key to providing high conversion efficiency. Chemical synthesis is usually employed for the preparation of various energy conversion active materials, which can be divided into four major categories in terms of reaction principles: thermochemistry, electrochemistry, mechanochemistry, and photochemistry. Among them, mechanochemistry is the study of chemical reactions induced by mechanical energy. [3] Mechanochemical syntheses can be carried out under a variety of conditions, such as at low temperatures, in inert or reactive atmospheres, under high gas pressures, in a solvent or under all-solid-state conditions. Thus, mechanochemical techniques are simple, versatile, and sustainable. Mechanochemistry can be used to develop new methods for some chemical reactions that are difficult to be realized by conventional chemical synthesis.Mechanochemistry was first reported with the development of grinding technology. As early as 315 B.C., Aristotle's students demonstrated for the first time that elemental Hg could be obtained by grinding cinnabar and acetic acid in a mortar. [4] For several decades, the development of mechanochemistry has become more comprehensive and systematic, and mechanochemical methods have been widely used in the fields of inorganic and organic materials, magnetic materials, and metallurgy. Mechanochemical equipment has evolved from the original manual mortar and pestle to a variety of novel mechanized instruments. Mechanochemical techniques including ballmilling, pan-milling, and ultrasonic irradiation have been successfully applied to prepare advanced functional materials for energy conversion and storage. However, most recent surveys/ reviews regarding mechanochemical technologies for material preparation are mainly focused on ball-milling. [3,[5][6][7][8] Recently, the unique advantages of mechanochemistry for energy storage and conversion applications have inspired Mechanochemistry with solvent-free and environmentally friendly characteristics is one of the most promising alternatives to traditional liquid-phase-based reactions, demonstrating epoch-making significance in the realization of different types of chemistry. Mechanochemistry utilizes mechanical energy to promote physical and chemical transformations to design complex molecules and nanostructured materials, encourage dispersion and recombination of multiphase components, and accelerate reaction rates and efficiencies via highly reactive surfaces. In particular, mechanochemistry deserves special attention because it is capable of endowing energy materials with unique characteristics and properties. Herein, the latest advances and progress in me...

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“…Ultrasonication can promote the dispersion of magnetic nanoparticles (MNPs) in reaction mixtures, leading to a larger active surface area that can catalyze reactions. [ 101 ]…”

Section: Categories Of Mechanochemistrymentioning

confidence: 99%

Section: Ultrasonication-induced Mechanochemistrymentioning

confidence: 99%

A Review on Mechanochemistry: Approaching Advanced Energy Materials with Greener Force

Liu

Zeng

et al. 2022

Advanced Materials

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“…Multicomponent reactions (MCRs) provide a powerful atom economy strategy in medicinal chemistry and organic synthesis. [1][2][3] Among diverse MCRs, the Biginelli reaction, which is derived from aldehyde, urea or thiourea, and β-keto ester in the presence of the catalytic amount of acid, indicates one of the most attractive and valuable multicomponent reactions owing to an extensive range of pharmacological and therapeutic applications of the produced 3,4-dihydropyrimidin-2(1H)-one (DHPM) derivatives. [4][5][6][7][8] Because of this, various synthetic methodologies using Lewis acid and Brønsted acid catalysts under different homogeneous conditions have been developed for the synthesis of DHPMs heterocyclic compounds.…”

Section: Introductionmentioning

confidence: 99%

Polymer/ZIF‐67 composite as an effective and recyclable nanocatalyst for Biginelli reaction

Houshiar

Rafiee

Grami

2022

Applied Organom Chemis

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Owing to their various functionalities and high processability, hybrid materials consisting of polymers and metal-organic frameworks have attracted interest in a variety of applications. In this study, the catalytic application of poly (amic acid) (PAA)/ZIF-67 nanocomposite in the Biginelli reaction was examined.First, PAA/ZIF-67 nanocomposite was fabricated and identified by Fouriertransform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, energy dispersive X-ray, simultaneous thermal analysis, and Brunauer-Teller techniques. The constructed composite was then utilized in the Biginelli reaction of various aldehydes with urea and ethyl acetoacetate under solventfree reaction conditions to afford dihydropyrimidones in high yields. This composite reveals outstanding catalytic activity, reproducible dispersibility, and stability. Also, PAA/ZIF-67 composite was efficiently recycled several times without a noticeable decrease in activity.

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“…Development in MCRs is notorious, especially over the last two decades [ 14 , 15 , 16 , 17 , 18 , 19 , 20 ]. Today we have, via these multicomponent transformations, rapid and one-pot access to diverse and complex libraries of bioactive compounds and to synthetic molecules with technological potentials [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

In Melting Points We Trust: A Review on the Misguiding Characterization of Multicomponent Reactions Adducts and Intermediates

et al. 2022

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We discuss herein the problems associated with using melting points to characterize multicomponent reactions’ (MCRs) products and intermediates. Although surprising, it is not rare to find articles in which these MCRs final adducts (or their intermediates) are characterized solely by comparing melting points with those available from other reports. A brief survey among specialized articles highlights serious and obvious problems with this practice since, for instance, cases are found in which as many as 25 quite contrasting melting points have been attributed to the very same MCR adduct. Indeed, it seems logical to assume that the inherent non-confirmatory nature of melting points could be vastly misleading as a protocol for structural confirmation, but still many publications (also in the Q1 and Q2 quartiles) insist on using it. This procedure contradicts best practices in organic synthesis, and articles fraught with limitations and misleading conclusions have been published in the MCRs field. The drawbacks inherent to this practice are indeed serious and have misguided MCRs advances. We therefore suggest some precautions aimed at avoiding future confusions.

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Greener organic synthetic methods: Sonochemistry and heterogeneous catalysis promoted multicomponent reactions

Abstract: Graphical abstract

Cited by 45 publications

References 245 publications

A Review on Mechanochemistry: Approaching Advanced Energy Materials with Greener Force

A Review on Mechanochemistry: Approaching Advanced Energy Materials with Greener Force

Polymer/ZIF‐67 composite as an effective and recyclable nanocatalyst for Biginelli reaction

In Melting Points We Trust: A Review on the Misguiding Characterization of Multicomponent Reactions Adducts and Intermediates

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