Ultrasonic Determination of the Effect of Casein Phosphopeptide-Amorphous Calcium Phosphate Paste on the Demineralization of Bovine Dentin

Yamaguchi, Kanako; Miyazaki, Masashi; Takamizawa, Toshiki; Inage, Hirohiko; Kurokawa, Hiroyasu

doi:10.1159/000099319

Cited by 39 publications

(33 citation statements)

References 15 publications

(9 reference statements)

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“…These results are consistent with our previous study using casein phosphopeptide-amorphous calcium phosphate to prevent demineralization. 24 The PRG filler extraction solution therefore appeared to prevent enamel demineralization. These results were supported by the absence of signs of demineralization in the PRG group according to SEM (Figure 3).…”

Section: Discussionmentioning

confidence: 99%

Effect of Pre-reacted Glass-ionomer Filler Extraction Solution on Demineralization of Bovine Enamel

Asano

Kawamoto

Iino

et al. 2014

Operative Dentistry

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Clinical RelevanceS-PRG filler extraction solution has an ability to protect the surface of enamel from demineralization. SUMMARYObjective: To determine the effect of pre-reacted glass-ionomer (PRG) filler extraction solution on the demineralization of bovine enamel by measuring changes in the ultrasound transmission velocity.Methods: The specimens were prepared by cutting bovine teeth into enamel blocks. The specimens were immersed in buffered lactic acid solution for 10 minutes twice a day, and then stored in artificial saliva. Other specimens were stored in PRG filler extraction solution for 10 minutes, followed by 10-minute immersion in the buffered lactic acid solution twice a day. The propagation time of longitudinal ultrasonic waves was measured by a pulser receiver. Six specimens were used for each condition, and analyses of variance followed by Tukey tests (a=0.05) were done.Results: No changes in sonic velocity were found for specimens stored in the PRG filler extraction solution, indicating that the PRG extraction solution had an effect on inhibiting the demineralization of bovine enamel. Conclusions:The results obtained with the use of an ultrasound measurement technique suggested that PRG filler extraction solution has the ability to prevent demineralization of enamel.

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Section: Discussionmentioning

confidence: 99%

Effect of Pre-reacted Glass-ionomer Filler Extraction Solution on Demineralization of Bovine Enamel

Asano

Kawamoto

Iino

et al. 2014

Operative Dentistry

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“…32 In a SEM in vitro study, adding CPP-ACP to a sports drink significantly reduced the beverage's erosivity, without altering the product's taste. 7,37 The mechanisms by which CPP-ACP reduces erosive tooth wear are unclear. However the finding that CPP-ACP increases hardness of enamel eroded by cola drink implies that its erosioninhibiting potential probably involves remineralization action.…”

Section: Groupsmentioning

confidence: 99%

Protective effect on enamel demineralization of a CPP–ACP paste: an AFM in vitro study

Poggio¹,

Lombardini²,

Dagna³

et al. 2009

Journal of Dentistry

106

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“…Pastes containing a complex of casein phosphopeptide (CPP) and amorphous calcium phosphate (ACP), with or without fluoride, have shown potential to prevent dental demineralization, increase remineralization in vitro (10)(11)(12)(13)(14) and to repair initial enamel caries lesions in vivo as well (15)(16)(17). It has been suggested that casein phosphopeptides (CPP) have the ability to stabilize calcium phosphate in solution by binding amorphous calcium phosphate (ACP) with their multiple phosphoserine residues, thereby allowing the formation of small CPP-ACP clusters (18).…”

Section: Introductionmentioning

confidence: 99%

Impact of Experimental Nano-HAP Pastes on Bovine Enamel and Dentin Submitted to a pH Cycling Model

et al. 2013

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This in vitro study evaluated the preventive potential of experimental pastes containing 10% and 20% hydroxyapatite nanoparticles (Nano-HAP), with or without fluoride, on dental demineralization. Bovine enamel (n=15) and root dentin (n=15) specimens were divided into 9 groups according to their surface hardness: control (without treatment), 20 Nanop paste (20% HAP), 20 Nanop paste plus (20% HAP + 0.2% NaF), 10 Nanop paste (10% HAP), 10 Nanop paste plus (10% HAP + 0.2% NaF), placebo paste (without fluoride and HAP), fluoride paste (0.2% NaF), MI paste (CPP-ACP, casein phosphopeptide-amorphous calcium phosphate), and MI paste plus (CPP-ACP + 0.2% NaF). Both MI pastes were included as commercial control products containing calcium phosphate. The specimens were treated with the pastes twice a day (1 min), before and after demineralization. The specimens were subjected to a pH-cycling model (demineralization-6-8 h/ remineralization-16-18 h a day) for 7 days. The dental subsurface demineralization was analyzed using cross-sectional hardness (kgf/mm 2 , depth 10-220 µm). Data were tested using repeated-measures two-way ANOVA and Bonferroni's test (p<0.05). The only treatment able to reduce the loss of enamel and dentin subsurface hardness was fluoride paste (0.2% NaF), which differed significantly from the control at 30-and 50-µm depth (p<0.0001). The other treatments were not different from each other or compared with the control. The experimental Nanop pastes, regardless of the addition of fluoride, were unable to reduce dental demineralization in vitro.

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Ultrasonic Determination of the Effect of Casein Phosphopeptide-Amorphous Calcium Phosphate Paste on the Demineralization of Bovine Dentin

Cited by 39 publications

References 15 publications

Effect of Pre-reacted Glass-ionomer Filler Extraction Solution on Demineralization of Bovine Enamel

Effect of Pre-reacted Glass-ionomer Filler Extraction Solution on Demineralization of Bovine Enamel

Protective effect on enamel demineralization of a CPP–ACP paste: an AFM in vitro study

Impact of Experimental Nano-HAP Pastes on Bovine Enamel and Dentin Submitted to a pH Cycling Model

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