Effect of Pre-reacted Glass-ionomer Filler Extraction Solution on Demineralization of Bovine Enamel

Abstract

Clinical RelevanceS-PRG filler extraction solution has an ability to protect the surface of enamel from demineralization. SUMMARYObjective: To determine the effect of pre-reacted glass-ionomer (PRG) filler extraction solution on the demineralization of bovine enamel by measuring changes in the ultrasound transmission velocity.Methods: The specimens were prepared by cutting bovine teeth into enamel blocks. The specimens were immersed in buffered lactic acid solution for 10 minutes twice a day, and then stored in artificial saliva. Other specimens were stored in PRG filler extraction solution for 10 minutes, followed by 10-minute immersion in the buffered lactic acid solution twice a day. The propagation time of longitudinal ultrasonic waves was measured by a pulser receiver. Six specimens were used for each condition, and analyses of variance followed by Tukey tests (a=0.05) were done.Results: No changes in sonic velocity were found for specimens stored in the PRG filler extraction solution, indicating that the PRG extraction solution had an effect on inhibiting the demineralization of bovine enamel. Conclusions:The results obtained with the use of an ultrasound measurement technique suggested that PRG filler extraction solution has the ability to prevent demineralization of enamel.

Evaluation of the caries‐preventive effect of toothpaste containing surface prereacted glass‐ionomer filler

“…Although all toothpaste formulations with active ingredients (fluoride or S‐PRG filler) significantly inhibited tooth demineralization relative to the untreated control, toothpaste containing S‐PRG filler rendered a higher percentage reduction of demineralization (Table ). These findings were consistent with those of previous studies that demonstrated that S‐PRG filler‐containing materials reduced biofilm formation and inhibited enamel demineralization . Although the toothpaste containing S‐PRG filler offered greater protection against demineralization relative to NaMFP‐containing toothpaste, only the formulations with S‐PRG filler 5% and 20% achieved the set effectiveness criterion of at least 20% statistically‐significant higher ∆z inhibition than the NaMFP toothpaste (only S‐PRG filler 20% with LD).…”

“…A dose response was observed with the S‐PRG filler dentifrices, with significant differences in both the level of ∆z and LD among the various concentrations of S‐PRG filler. Thus, increasing the concentration of S‐PRG filler could lead to the total inhibition of demineralization, considering its multiple actions of antibiofilm effect, acid neutralizing effect, and enhancing tooth resistance to acid attack . This calls for further investigation, and preferably, clinical trials.…”

“…Surface prereacted glass-ionomer (S-PRG) filler, the active ingredient in commercially-available GIOMER products (SHOFU, Kyoto, Japan), has been researched in many forms, including pits/fissure sealants, denture base resin, composite resins, and resin barrier coats. [12][13][14][15][16][17][18][19][20][21][22] These studies indicate that S-PRG filler has the capability to release and recharge fluoride, [12][13][14] reduce biofilm formation, 15,16 inhibit enamel demineralization, [17][18][19] and remineralize initial caries lesions. 20 Besides fluoride, these fillers release multiple other ions, such as strontium (Sr 2+ ), sodium (Na + ), Boron (BO 3…”

Ultrasonic assessment of the effects of self-assembling peptide scaffolds on preventing enamel demineralization

“…Differences in ultrasonic velocity may be related to variations in the degree of mineralization, because the ultrasonic velocity increases proportionally with the volumetric concentration of minerals [11]. Ultrasonic velocity has also been shown to be an index of remineralization and demineralization because of its relation to the mineral content of the tooth substrate [12,13]. When enamel remineralization occurs, both mineral concentration and ultrasonic velocity increase.…”

Three-year clinical evaluation of posterior composite restorations placed with a single-step self-etch adhesive

“…Multi ion-releasing resin composite containing surface-prereacted glass ionomer (S-PRG) filler has been developed for dental applications (9)(10)(11)(12). This S-PRG filler has a layered structure consisting of a fluoroboroaluminosilicate glass core, reacted layers forming a glass ionomer phase on the surface of the core, and a reinforced layer covering the surface of the prereacted phase (13,14).…”