Ultrasensitive electrochemical immunoassay for melanoma cells using mesoporous polyaniline

Abstract

We report the development of an antibody (anti-MC1R antibody)-functionalized polyaniline nanofibers modified screen-printed electrode capable of efficient electrochemical detection of melanoma cells at levels (1 cell per mL) not readily achieved by other methods. This immunosensor is highly selective in its detection of melanoma cells over normal human cells.

Cranberry Proanthocyanidins-PANI Nanocomposite for the Detection of Bacteria Associated with Urinary Tract Infections

“…The biosensor was prepared by a two-step methodology. In the first step, PANI nanofibers were drop-cast on the SPE to obtain PANI/SPE, as previously described by Prathap et al (2018) [18]. PANI nanofibers were prepared through a modified interfacial polymerization method at the interface of two immiscible solvents: chloroform and water.…”

Electrochemical Sensor Platforms Based on Nanostructured Metal Oxides, and Zeolite‐Based Materials

“…Electrochemical analysis of lindane shows that lindane could be reduced electrochemically via 6 electrons process to form benzene. A voltammetric study of the electrochemical behavior at CuO‐MnO 2 in methanol−water exhibited a single irreversible peak that represents a total six‐electron response in the linear range of 1–700 μM with the sensitivity of 0.12 μA μM −1 cm −2 and a LOD of 4.8 nM …”

“…A voltammetric study of the electrochemical behavior at CuO-MnO 2 in methanolÀwater exhibited a single irreversible peak that represents a total six-electron response in the linear range of 1-700 mM with the sensitivity of 0.12 mA mM À1 cm À2 and a LOD of 4.8 nM. [115] Rajendra and co-authors have reported a novel electrochemical lindane sensor based on NiCo 2 O 4 hierarchical nanomicrostructures. [116] Polarographic analysis of lindane exhibited a single well-defined six-electron irreversible reduction peak at reduction potential ofÀ1.5 V (vs Ag/AgCl) (Figure 6).…”

Self‐doped N‐propansulfonic acid polyaniline‐polyethylene terephthalate film used as active sensor element for humidity or gas detection

“…One of the most serious problems that affect environment stability and human population is contaminations with different toxic gases, such as carbon monoxide, carbon dioxide, ammonia, acetone, liquefied petroleum gas, and so on, which provokes respiratory, sensorial, and cardiovascular disorders, as well as atmospheric pollution . Hence, precise detection of these gases sensors, as well as humidity sensors, is very important, especially for environment, industry, and people's health …”

“…[9][10][11] Hence, precise detection of these gases sensors, as well as humidity sensors, 12 is very important, especially for environment, industry, and people's health. [13][14][15][16][17][18] A lot of attention is devoted to polyaniline (PANi), one of the most promising conducting polymers, candidate for application of gas and humidity sensing, due to its properties such as unique conductivity and chemical stability in the environment. 14,[19][20][21][22][23][24][25][26] However, the PANi is intractable, infusible, and insoluble, and these inconveniences hamper greatly the processing and applications of the polymer.…”