Ultrafast synthesis of gold nanosphere cluster coated by graphene quantum dot for active targeting PA/CT imaging and near-infrared laser/pH-triggered chemo-photothermal synergistic tumor therapy

Ye, Xuan; Zhang, Ruo‐Yun; Zhao, Donghui; Zhang, Xiaoshuai; An, Jie; Cheng, Kai; Hou, Xiaolin; Song, Xianlin; Zhao, Yuan‐Di; Yang, Xiaoquan

doi:10.1016/j.cej.2019.03.035

Cited by 52 publications

(26 citation statements)

References 38 publications

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“…For example, MRI has high spatial resolution but limited sensitivity, whereas FI has excellent sensitivity but lacks spatial and anatomical resolution 69 , 70 . Dual-mode imaging can significantly improve the efficiency of tumor diagnosis by compensating for the limitations of each mode 71 , 72 . Several multi-mode imaging methods have been developed in recent years to improve the accuracy of early cancer diagnosis 44 , 73 .…”

Section: Image-guided Immunotherapymentioning

confidence: 99%

Tumor immunotherapy and multi-mode therapies mediated by medical imaging of nanoprobes

Yang¹,

Guan²,

Zhang³

2021

Theranostics

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Immunotherapy is an effective tumor treatment strategy that has several advantages over conventional methods such as surgery, radiotherapy and chemotherapy. Studies show that multifunctional nanoprobes can achieve multi-mode image-guided multiple tumor treatment modes. The tumor cells killed by chemotherapies or phototherapies release antigens that trigger an immune response and augment the effects of tumor immunotherapy. Thus, combining immunotherapy and multifunctional nanoprobes can achieve early cancer diagnosis and treatment. In this review, we have summarized the current research on the applications of multifunctional nanoprobes in image-guided immunotherapy. In addition, image-guided synergistic chemotherapy/photothermal therapy/photodynamic therapy and immunotherapy have also been discussed. Furthermore, the application potential and clinical prospects of multifunctional nanoprobes in combination with immunotherapy have been assessed.

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Section: Image-guided Immunotherapymentioning

confidence: 99%

Tumor immunotherapy and multi-mode therapies mediated by medical imaging of nanoprobes

Yang¹,

Guan²,

Zhang³

2021

Theranostics

Self Cite

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“…Body weight monitoring, hematoxylin and eosin (H&E) staining of organs, and blood biochemical indicators demonstrated the good safety and low toxicity of the probe aer injection. 379 Badrigilan et al synthesized nanoparticles from super paramagnetic iron oxide (SPIO) and bismuth oxide (Bi 2 O 3 ) and they coated them with GQDs for use as in vitro CT/MR dualmodal biomedical imaging probes and for cancer-specic PTT. These nanocomposites showed strong light absorbance with a wide-band in the NIR region.…”

Section: O-dots In Phototherapymentioning

confidence: 99%

Organic dots (O-dots) for theranostic applications: preparation and surface engineering

et al. 2021

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“…Apart from the high absorbance, GQDs could be developed for photoacoustic imaging (PAI) or combined with other imaging contrast agents to achieve multimodal imaging-guided cancer therapy [193,194]. In Xuan's work [195], a versatile nano-probe based on GQDs and Au nanodots was formed for PAI and computed tomography (CT) imaging. This nanoprobe displayed great PTC efficiency as high as 51.3% with relatively low cytotoxicity observed.…”

Section: Graphene-based Nanomaterialsmentioning

confidence: 99%

Recent advance in near-infrared/ultrasound-sensitive 2D-nanomaterials for cancer therapeutics

et al. 2020

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In recent years, the emerging two-dimensional (2D) nanomaterials have shown great potential for a variety of applications such as electronics, catalysis, supercapacitors, and energy materials. In the biomedical arena, these nanomaterials, especially 2D-ultrathin nanomaterials, have also been regarded as promising nano-carriers and/or diagnostic agents for cancer diagnosis and treatment, owing to their remarkable mechanical, photothermal, and optical properties. In this review, we provide the recent development of the nanoplatforms based on near-infrared/ultrasound-sensitive 2D-materials, representatively such as graphdiyne (GDY), black phosphorus, transition metal dichalcogenides (TMDs), and antimonene, for non-invasive cancer therapeutics including photothermal, photodynamic and sonodynamic approaches. The general properties of these 2D nanomaterials linking to biomedical interests are first introduced, followed by the fabrication processes of diverse nano-platforms and related outcomes of cancer diagnosis and treatments. We also outline the current challenges and prospects of the 2D materials for non-invasive approaches to cancer treatments in the future.

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Ultrafast synthesis of gold nanosphere cluster coated by graphene quantum dot for active targeting PA/CT imaging and near-infrared laser/pH-triggered chemo-photothermal synergistic tumor therapy

Cited by 52 publications

References 38 publications

Tumor immunotherapy and multi-mode therapies mediated by medical imaging of nanoprobes

Tumor immunotherapy and multi-mode therapies mediated by medical imaging of nanoprobes

Organic dots (O-dots) for theranostic applications: preparation and surface engineering

Recent advance in near-infrared/ultrasound-sensitive 2D-nanomaterials for cancer therapeutics

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