Uji daya hambat ekstrak rimpang kunyit (Curcuma longa) terhadap pertumbuhan bakteri Staphylococcus aureus dan Pseudomonas sp.

Pangemanan, Andrew; Fatimawali, Fatimawali; Budiarso, Fona

doi:10.35790/ebm.4.1.2016.10840

Cited by 11 publications

(10 citation statements)

References 5 publications

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“…In addition, tannins also play a role in wound healing by increasing the re-formation of dermis tissue in wound tissue (fibroplasia) (kurnianto). In addition, the alkaloids contained in turmeric extract (Curcuma Longa) can inhibit bacterial growth by interfering with peptidoglycans in bacterial cells that cause the formation of cell walls (Kumara, Sri Pradnyani and Sidiarta, 2019); (Pangemanan, . and Budiarso, 2016).…”

Section: Figure 1 Wound Length Reduction Graphmentioning

confidence: 99%

Effectiveness of Turmeric Ethanol Extract Cream Preparation (Curcuma Longa) in Speeding up Wound Healing in Male Wistar Rats

Ling

Florenly

Liena

et al. 2021

birex. budapest. internation. research. in. exact. science

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Injury is the loss or damage of some body tissues, due to a factor that interferes with the body's protective system. The results of several studies state turmeric rhizome extract is effective in wound healing. This study aims to find out the effect of turmeric extract (Curcuma longa) on wound healing in white rats. This type of research is experimental with the approach of Pre-test and Post-test group only control design, conducted November to December 2020. The samples used were turmeric rhizomes (Curcuma Longa) and male white rats. Determination of the size of the sample according to Federer's formula, so that the number of samples as many as 25 mice, the division of 4 treatment groups and 1 control group. The results of the study from the Anova test obtained a Sig value. Calculate 0.000 while sig value (α) is 0.05 which means sig value. Count sig < (α). This means that there is a real influence of the administration of turmeric extract (Curcuma Longa) on the healing of sores in mice. Turmeric ethanol extract (Curcuma Longa) has several bioactive compounds such as alkaloids, flavonoids, saponins, and tannins that play a role in wound healing. The optimum concentration of turmeric ethanol extract (Curcuma Longa) that can cure sores in white rats is 5%. The highest percentage of cures on k-14 days was in the positive control (Bioplacenton®) which was 95% and followed by extract 5% v/ v with a cure percentage of 90%. The creamy preparation of turmeric ethanol extract (Curcuma Longa) has an ability that is close to Bioplacenton® in healing wounds in mice.

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Section: Figure 1 Wound Length Reduction Graphmentioning

confidence: 99%

Effectiveness of Turmeric Ethanol Extract Cream Preparation (Curcuma Longa) in Speeding up Wound Healing in Male Wistar Rats

Ling

Florenly

Liena

et al. 2021

birex. budapest. internation. research. in. exact. science

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“…Warnaini (2013) melaporkan hasil diameter zona hambat pada konsentrasi 15% sebesar 11mm, konsentrasi 30% sebesar 12,3mm, konsentrasi 50% sebesar 13,3mm, konsentrasi 75% sebesar 13,7 mm dan konsentrasi 100% sebesar 14,7mm (Warnaini, 2013). Pangemanan (2016) juga melakukan penelitian yang menguji aktivitas antibakteri ekstrak rimpang kunyit terhadap bakteri Staphylococcus aureus (Gram positif) (Pangemanan, 2016).…”

Section: Pembahasanunclassified

“…Hasil penelitian Pangemanan (2016) menunjukkan bahwa ekstrak rimpang kunyit dengan konsentrasi 5%, 10%, 20%, dan 40% dapat menghambat pertumbuhan Staphylococcus aureus dengan rerata masing-masing 11 mm, 13,5mm, 14,5mm dan 15mm (Pangemanan, 2016). Penelitian yang dilakukan oleh Mohammed (2015) mengenai aktivitas antibakteri kurkumin terhadap bakteri Gram positif Streptococcus mutans dan Streptococcus pyogenes, masing masing dengan zona hambat sebesar 9,7mm dan 10,2mm (Mohammed, 2015).…”

Section: Pembahasanunclassified

Uji Efektivitas Antibakteri Ekstrak Rimpang Kunyit (Curcuma domestica Val.) terhadap Pertumbuhan Propionibacterium acnes In Vitro

Cahyani

Anggraini

Soleha

et al. 2020

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One of the treatments for acne vulgaris therapy is antibiotics, it can be applied topically and systemically. However, long-term and inappropriate use of antibiotics can increase the incidence of antibiotic drug resistance. Some medicinal plants are known to have antimicrobial properties, one of them is turmeric rhizome. Turmeric rhizome is known to contain essential oils and curcumin so that it can be useful as an antibacterial, antiviral, anti protozoa, anti-inflammatory, antioxidant, and antineoplasm. This study aims to determine the effectiveness of the antibacterial turmeric extract against the growth ofÂ Propionibacterium acnes. The type of this research is an experimental laboratory with disc diffusion method on Mueller Hinton Agar media. Turmeric extract was obtained from the Laboratory of Organic Chemistry at the University of Lampung with maceration techniques using 96% ethanol. Turmeric rhizome extract is divided into several concentrations namely 15%, 30%, 50%, 75%, and 100%. As negative control is aquades and positive control is clindamycin. Data was obtained based on the result of measurement Diameter of inhibition zone made through paper discs and measured by calipers. The data were analyzed by using One Way ANOVA. The result of this study indicated that the diameter of the inhibits zone at a concentration of 15%, 30%, 50%, 75%, and 100%. Sequentially is 11,35mm, 15,65mm, 17,575mm, 18,85mm, and 20,8mm. in the negative control is 0 mm and positive control is 28,1 mm (score p-value=0,000). There is antibacterial effectiveness of turmeric extract against the growth ofÂ Propionibacterium acnesÂ in vitro, but it is no superior compared with clindamycin phosphate.

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“…Hasil dari penelitian tersebut menunjukkan bahwa ekstrak kunyit konsentrasi 5%, 10%, 20%, dan 40% dapat menghambat pertumbuhan bakteri Staphylococcus aureus dan Pseudomonas sp. 11 Efektivitas daya hambat ekstrak kunyit terhadap pertumbuhan bakteri Streptococcus mutans belum pernah diteliti sebelumnya. Berdasarkan latar belakang di atas, penulis tertarik untuk meneliti efektivitas daya hambat ekstrak kunyit konsentrasi 5%, 10%, 20%, dan 40% terhadap pertumbuhan bakteri Streptococcus mutans.…”

Section: Uji Efektivitas Ekstrak Kunyit (Curcuma Longa) Terhadap Dayaunclassified

Uji efektivitas ekstrak kunyit (Curcuma longa) terhadap daya hambat pertumbuhan bakteri Streptococcus mutans

Kumara

Pradnyani

Sidiarta

2019

Intisari Sains Medis

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Background: Dental caries is a multifactorial disease characterized by dental tissue damage caused by the production of bacterial acids. The bacteria play the most role in the occurrence of caries is Streptococcus mutans. Turmeric extract (Curcuma longa) has been studied can inhibit bacterial growth because it contains essential oils and curcumin. The purpose of this study was to determine the inhibitory power of turmeric extract 5%, 10%, 20%, and 40% on the growth of Streptococcus mutans bacteria. Methods: Studies with true experimental design using a post test only control group design have been carried out on Streptococcus mutans bacteria. Turmeric extract was made by maceration method into 96% ethanol so that the required concentration was obtained (5%, 10%, 20%, dan 40%). The inhibition testing is done by the disk-diffusion method. Data were analyzed using the Kruskal-Wallis test on SPSS version 20 due to the data were not normally distributed. Results: The results showed that phytochemical assessment of turmeric extract showed positive results on phenol, essential oil, saponins, tannins, and flavonoids. The average value of the inhibitory zone diameter of Streptococcus mutans bacteria formed in turmeric extract concentrations of 5%, 10%, 20%, and 40% is 0 mm where there are significant differences compared to positive controls (P < 0.05) Conclusion: Various doses of turmeric extract couldn't inhibit the growth of Streptococcus mutans bacteria

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Uji daya hambat ekstrak rimpang kunyit (Curcuma longa) terhadap pertumbuhan bakteri Staphylococcus aureus dan Pseudomonas sp.

Cited by 11 publications

References 5 publications

Effectiveness of Turmeric Ethanol Extract Cream Preparation (Curcuma Longa) in Speeding up Wound Healing in Male Wistar Rats

Effectiveness of Turmeric Ethanol Extract Cream Preparation (Curcuma Longa) in Speeding up Wound Healing in Male Wistar Rats

Uji Efektivitas Antibakteri Ekstrak Rimpang Kunyit (Curcuma domestica Val.) terhadap Pertumbuhan Propionibacterium acnes In Vitro

Uji efektivitas ekstrak kunyit (Curcuma longa) terhadap daya hambat pertumbuhan bakteri Streptococcus mutans

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