Uji Aktivitas Antibakteri Ekstrak Kasar Bawang Putih (Allium sativum ) terhadap Bakteri Shigella dysenteriae yang Resisten terhadap Ampisilin

Abstract

Background : Gastrointestinal infections, especially caused by Shigella dysenteriae bacteria is still a health issue in Indonesia. The number of ampicillin resistance to S. dysenteriae has been widely reported. Garlic (Allium sativum) is a traditional medicine that efficacy as an antibacterial. Garlic contains an organosulfur compound Allicin. Research Purpose: This study aimed to determine the antibacterial activity of garlic rule extract on the growth of S. dysenteriae bacteria that are resistant to ampicillin. Research Methods: This study used the experimental with post test only control group design. The antibacterial activity test was determined based on the diameter of clear zone formed. Test were performed on garlic filtrate, ciprofloxacin as a positive control and aquades as a negative control. Each treatment was performed three times. Research Result: This research showed that rule extract of garlic (A. sativum) had a clear zone against S. dysenteriae that was resistant to ampicillin. Conclusion: The conclusion of this research was that rule extract of garlic (A. sativum) had an antibacterial activity against S. dysenteriae which resistant to ampicillin. Keywords : Antibacterial activity, Garlic (A. sativum), S. dysenteriae

Effectiveness of Wresah (Amomum Dealbatum) Extract in Inhibiting the Growth of Staphylococcus Aureus

“…Not only in Indonesia, in developed countries, such as the United States, there are 20,000 deaths every year due to nosocomial infections (Tandanu, 2020). Worldwide, 10% of hospital inpatients experience new infections during their stay, totaling 1.4 million infections each year (Salim & Soleha, 2017). According to WHO in 55 hospitals in 14 countries around the world, 8.7% of hospital patients suffer from infections during hospitalization (Roni et al, 2019).…”