Diabetes mellitus (DM) or diabetes is a disease caused by disorders related to the hormone insulin. Ginger, lemongrass and cinnamon are traditional plants that have the potential to be developed as herbal medicines. The combination of these traditional plants can be used as an alternative treatment for diabetes mellitus. Infusions of ginger, lemongrass and cinnamon contain secondary metabolites, namely flavonoids, terpenoids and tannins. These three active compounds have antioxidant, antidiabetic, and anti-inflammatory activities. The aim of this study was to determine the antidiabetic effect of the infusion of a combination of JSKM (ginger (Zingiber officinale), lemongrass (Cymbopogon citratus) and cinnamon (Cinnamomum verum)) on male mice (Mus Musculus). The design of this research is experimental with data analysis method using SPSS 16.0. Observation of healing time is done by observing the decrease in blood sugar levels for 7 days. In this study, 5 treatment groups were used, namely the negative control group (aquadest), the positive control group (glibenclamide), the P1 dose (162 mg/kgBW), the P2 dose (324 mg/kgBW), and the P3 dose (486 mg/kgBW). The most effective dose of the antidiabetic effect of JSKM infusion in male mice was in the P3 group with a dose of 486 mg mg/kgBW.
Wresah plant (Amomum dealbatum) is one of the typical fruit species from Lombok Island which has a distinctive fragrance and is a member of the ginger-ginger tribe. This study aims to test the ethanol extract of Wresah skin (Amomum dealbatum) as an antibacterial (Staphylococcus aureus) with concentrations of 15%, 30% and 50%. The research method conducted was laboratory experimental. The antibacterial test of Staphyloccocus aureus was carried out with five treatment groups and five repetitions, namely positive control (ciprofloxacin), negative control (distilled water), concentrations of 15%, 30% and 50% using well method and then incubated for 24 hours at a temperature of 370 C. The results of the antibacterial test of ethanol extract of Wresah fruit peel showed inhibition of Staphylococcus aureus bacteria and at concentrations of 15%, 30%, and 50% which produced the largest diameter of the inhibition zone with an average diameter of 2.0 mm. The Kruskal Wallis test showed a statistically significant difference between the three concentrations tested (p < 0.05), which means that Wresah fruit peel extract is able to inhibit the growth of Staphylococcus aureus bacteria. In conclusion, the extract of Wresah fruit peel has demonstrated antibacterial properties against Staphylococcus aureus and can be used as a natural alternative to conventional antibiotics.
Background: The hospital pharmacy installation is a health service unit that is required to provide professional services and improve quality which is oriented towards achieving patient satisfaction. Waste identification in pharmaceutical services is important because it has an impact on stakeholder satisfaction. Objective: Identifying waste using the DOWNTIME method for the outpatient prescription services at the pharmacy installation of Rumah Sakit Islam Siti Hajar Mataram. Methods: The study used the cross-sectional design, with the population being all outpatients who were provided with pharmaceutical services during February – April 2019 as well as all staff. Data were tabulated and analyzed descriptively. Critical waste was obtained through questionnaires and the root causes of critical waste were obtained through in-depth interviews with 5-why methods. Results: Waste waiting had the highest rate compared to other wastes, reaching 44% or 53 out of 121 respondents, followed by inventory (26%), extra processing (19%), transportation (14%), defects (14%), motion (13%), over production (8%), and non-utilized skills (7%). Meanwhile, from the staff respondents, waiting was also the highest waste (18%), followed by inventory (16%), motion (13%), over production (12%), transportation (12%), non-utilized skills (10%), extra processing (10%), and defects (9%). The root cause of waste waiting was the frequent drug unavailability due to delays in payment of services from the cooperating party to the hospital as well as the narrow service areas. Conclusion:Waste waiting became the critical waste with the highest percentage of dissatisfaction in the patient respondents (44%) and staff respondents (18%). Keywords: Waste, DOWNTIME, outpatient prescription services, pharmacy installation of RSI Siti Hajar Mataram
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