Soci6t6 suisse de chimie, B&le -Societ& svizzera di chimica, Basilea Nachdruck verboten -Tous droits rCservCs -Printed by Birkhauser AG., Basel, Switzerland
Summary.A novel synthesis for rac-pilosinine (6 rac) and transformation of ( + )-pilosinine (6) into the pilocarpus alkaloids (+)-isopilosine (9) and (+)-pilocarpine (15) are described. By correlation via 6 with 15 the absolute configuration of (+)-isopilosinc (9) is established.Von den funf aus Pilocarpus-Arten isolierten Imidazol-Alkaloiden l), die teils der cis-Reihe, teils der thermodynamisch stabileren trms-(= iso-) 2)-