Über die Bedeutung der Pumarsäure für die tierische Gewebsatmung. - III. Mitteilung.

THE EXCRETION OF l-MALIC ACID IN RELATION TO THE TRICARBOXYLIC ACID CYCLE IN THE KIDNEY*

“…In attempting to design further experiments to clarify the nature of this difference. we were reminded of the catalytic "sparking" effect of fumarate in isolated tissues oxidizing pyruvate (14,15). We wondered whether fumarate could exert a similar catalytic effect on malate reabsorption by "sparking" the oxidative energy production in the renal tubular cells.…”

Pyruvate oxidation in ox heart

“…It does not affect the completeness of the pyruvate oxidation, since even without added fumarate complete oxidation takes place. It would appear, therefore, that animal tissues differ in this respect, heart and possibly pigeon breast muscle (Krebs & Eggleston, 1940) contrasting with brain (Long, 1946) and liver (Annau et al 1936).…”

A history of research on yeasts 6: the main respiratory pathway

“…In the 1920s, Thorsten Thunberg6 had suggested a scheme for carbohydrate oxidation (Figure 3). Important advances in understanding this pathway were, however, not made until the 1930s, and were due to Albert von Szent‐Györgyi7 and his colleagues 1, 171, who were working on pigeon breast muscle, which respires at a high rate and produces very little lactic acid.…”