A history of research on yeasts 6: the main respiratory pathway

Barnett, James A.

doi:10.1002/yea.1021

Cited by 30 publications

(20 citation statements)

References 139 publications

(108 reference statements)

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“…In 1913, Carl Neuberg (born July 29, 1877, in Hannover, Germany; died May 30, 1956, in New York) considered the glycolytic breakdown of the glucose molecule to be achieved through the formation of a methylglyoxal intermediate (1). Although this concept ultimately turned out to be incorrect, it dominated the thinking of the research community for many years (2).…”

Section: History Of Glycolysis Researchmentioning

confidence: 99%

“…Nevertheless, as Carl Cori mentioned later, progress in the research field was delayed by the "persistence of many wrong leads" (2). After Embden's sudden death in 1933, other researchers, in particular Otto Meyerhoff (born April 12, 1884, in Hannover; died October 6, 1951, in Philadelphia) and Jakub Parnas (born January 16, 1884, in Mokrinay/Drohobych, Ukraine, near Lviv; died January 29, 1949, in Moscow), proceeded with experimental work on glycolysis, and within a few years, the steps involved in the phosphorylating degradation of glucose as known today were fully elucidated (1,2). This is why the glycolytic pathway is also known as the Embden-Meyerhof or Embden-MeyerhofParnas pathway.…”

Section: History Of Glycolysis Researchmentioning

confidence: 99%

“…Glycolysis was the first important metabolic pathway elucidated between 1913 and 1938 (1). Metabolic flux is typically regulated during the initial steps of a metabolic pathway (for review, see Ref.…”

Section: History Of Glycolysis Researchmentioning

confidence: 99%

“…This minireview is dedicated to the memory of the distinguished biochemist Professor Richard W. Hanson. 1 To whom correspondence should be addressed. E-mail: lenzen.sigurd@mh-hannover.de.…”

Section: History Of Glycolysis Researchmentioning

confidence: 99%

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A Fresh View of Glycolysis and Glucokinase Regulation: History and Current Status

Lenzen

2014

Journal of Biological Chemistry

126

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This minireview looks back at a century of glycolysis research with a focus on the mechanisms of flux regulation. Traditionally, glycolysis is regarded as a feeder pathway that prepares glucose for further catabolism and energy production. However, glycolysis is much more than that, in particular in those tissues that express the low affinity glucose-phosphorylating enzyme glucokinase. This enzyme equips the glycolytic pathway with a special steering function for the regulation of intermediary metabolism. In beta cells, glycolysis acts as a transducer for triggering and amplifying physiological glucose-induced insulin secretion. On the basis of these considerations, I have defined a glycolytic flux regulatory unit composed of the two fructose ester steps of this pathway with various enzymes and metabolites that regulate glycolysis.

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Section: History Of Glycolysis Researchmentioning

confidence: 99%

Section: History Of Glycolysis Researchmentioning

confidence: 99%

Section: History Of Glycolysis Researchmentioning

confidence: 99%

“…This minireview is dedicated to the memory of the distinguished biochemist Professor Richard W. Hanson. 1 To whom correspondence should be addressed. E-mail: lenzen.sigurd@mh-hannover.de.…”

Section: History Of Glycolysis Researchmentioning

confidence: 99%

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A Fresh View of Glycolysis and Glucokinase Regulation: History and Current Status

Lenzen

2014

Journal of Biological Chemistry

126

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“…Glycolysis is a universal metabolic pathway that converts glucose into pyruvate with the concomitant production of a relatively small amount of ATP. This pathway probably developed before there was sufficient oxygen in the atmosphere to sustain more-effective methods of energy extraction (Barnett, 2003). When aerobic organisms evolved, a more-efficient energy-harvesting pathway, namely the tricarboxylic acid (TCA) cycle, developed; oxidative phosphorylation steps were added onto glycolysis (Barnett, 2003).…”

Section: Congruence Of the Ribosomal Protein Tree With Other Protein mentioning

confidence: 99%

Phylogenetic positions of ‘Candidatus Phytoplasma asteris' and Spiroplasma kunkelii as inferred from multiple sets of concatenated core housekeeping proteins

Zhao

Davis

Lee

2005

International Journal of Systematic and Evolutionary Microbiology

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Phytopathogenic mollicutes, which include spiroplasmas and phytoplasmas, are cell wall-less bacteria that parasitize plant hosts and insect vectors. Knowledge of the evolution of these agents is important in understanding their biology. The availability of the first complete phytoplasma and several partial spiroplasma and phytoplasma genome sequences made possible an investigation of evolutionary relationships between phytopathogenic mollicutes and other micro-organisms, especially Gram-positive bacteria, using a comparative genomics approach. Genome data from a total of 41 bacterial species were used in the analysis. Sixty-one conserved proteins were selected from each species for the construction of a hypothetical phylogenetic tree. The genes encoding these selected proteins are among a core of genetic elements that constitute a hypothetical minimal genome. The proteins were concatenated into five superproteins according to their functional categories, and phylogenetic trees were reconstructed using distance, parsimony and likelihood methods. Phylogenetic trees based on the five sets of concatenated proteins were congruent in both clade topology and relative branching length. Spiroplasma kunkelii and phytoplasmas clustered together with other mollicutes, forming a monophyletic group. Phytoplasmas diverged from spiroplasmas and mycoplasmas at early stages in the evolution of mollicutes. Branch lengths on the phylogenetic trees were noticeably longer in the Mollicutes clade, suggesting that the genes encoding the five sets of proteins evolved at a greater rate in this clade than in other clades. This observation reinforces the concept that mollicutes have rapidly evolving genomes.

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Production and purification of xylitol by Scheffersomyces amazonenses via sugarcane hemicellulosic hydrolysate

Silva

Dussán

Idarraga

et al. 2020

Biofuels Bioprod Bioref

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Xylitol was produced by Scheffersomyces amazonensis UFMG‐HMD‐26.3 in hemicellulosic hydrolysate obtained from a mixture of sugarcane bagasse and straw (1:1) in batch fermentation, and was recovered using supercritical fluid. The xylitol produced was 20.11 g L−1 and the extraction approach reached a xylitol recovery of 40.51% at a high purity level of 99.59%. An analysis of energy consumption for the xylitol production process showed that xylitol production from sugarcane biomass hemicellulosic hydrolysate is feasible, highlighting the potential use of this biomass in sustainable xylitol production and supercritical fluids as a robust proposal for xylitol separation. © 2020 Society of Chemical Industry and John Wiley & Sons, Ltd

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A history of research on yeasts 6: the main respiratory pathway

Abstract: The cell knows two methods of getting out the energy of [foodstuff] molecules; it either fragments them or burns them. The first method we refer to as fermentation, the second, oxidation (von Szent-Györgyi, 1937 [172] p. 165).

Cited by 30 publications

References 139 publications

A Fresh View of Glycolysis and Glucokinase Regulation: History and Current Status

A Fresh View of Glycolysis and Glucokinase Regulation: History and Current Status

Phylogenetic positions of ‘Candidatus Phytoplasma asteris' and Spiroplasma kunkelii as inferred from multiple sets of concatenated core housekeeping proteins

Production and purification of xylitol by Scheffersomyces amazonenses via sugarcane hemicellulosic hydrolysate

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