Über das Verhalten der unveresterten Fettsäuren und des Glycerins im Hungerzustand, nach Glucose- und Fructosegaben

Eymer, K. P.; Schwarz, K.; Weinges, K. F.

doi:10.1007/978-3-642-96028-4_129

Cited by 2 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Fastenperioden ffihren zu erheblichen Anstiegen der FFS-Spiegel als Ausdruck vermehrter Lipolyse bei eingeschrgnkter Rfickveresterung [14,19,23,31,35,80,82,83]. Dieser Anstieg naeh Fasten ist bei Adip6sen mit und ohne Kohlenhydrattoleranzst6rung prozentual geringer ausgeprggt als bei Normalpersonen [35].…”

Section: Dislcussionunclassified

“…Der yon uns unter Reduktionsdigt beachtete erhebliehe AbfM1 des freien Glycerins im Nfichternserum bei gleiehzeitigem leiehten Anstieg der freien Fettsguren mit Normalisierung des Quotienten FFS/Glyecrin ist damit wahrscheinlieh nieht nur Ms Ausdruok einer partiellen Normalisierung der erhShten Basallipolyse des Ubergewichtigen zu deuten, sondern kSnnte aueh ffir eine unter diesen Umstgnden gesteigerte Verwertung des Glycerins in der Peripherie spreehen [23].…”

Section: Dislcussionunclassified

See 1 more Smart Citation

Einflu� der Gewichtsreduktion auf Metabolite des Kohlenhydrat- und Fettstoffwechsels und auf das Verhalten des Seruminsulins bei Adipositas

et al. 1968

View full text Add to dashboard Cite

Influence of weight reduction on carbohydrate and fat metabolism and on serum insulin response in obesitySummary. To find out which of the metabolic changes observed in obesity are reversible by a reducing diet, we examined 37 obese out-patients with a mean overweight of 71~o B~ocA. A manifest diabetes mellitus and endocrine diseases were excluded by clinical means. 20 subjects showed disturbances of carbohydrate-tolerance. Oral and i.v. glucose-tolerance tests gave normal results in 17. Both subgroups were put on a 1000 cal. mixed diet and had mean weightdosses of 21.2, vs. 17.5 kg, corresponding to 34% vs. 28% BROCA, i.e. less than half of their overweight. --The following changes were observed in the subgroup with impaired carbohydrate-tolerance: --1. Significant improvement of glucose-tolerance with beginning normalization of fasting blood sugar, 120' value after oral glucose and of the k-values for i.v. and oral glucose-tolerance tests. --2. Highly significant reduction of the elevated fasting values for free serum glycerol with normalization of the quotient: free fatty acids/glycerol in fasting serum. --3. Significant fall of the high levels for insulin-like activity and for immunologically reacting insulin. --Under identical conditions the subgroup with normal carbohydrate-tolerance showed only a moderate increase of free fatty acids 90' and 120' after glucose. In the obese group as a whole, we found a reduction of serum esterified fatty acids under low calorie diet. --The changes described under 1--3 were more pronounced with this dietary treatment than in fasting periods generally described until now, and occurred predominantly in the subgroup with impaired carbohydrate-tolerance. Our findings indicate that hyperinsulinism held responsible for obesity up to now by some authors is probably adaptire.

show abstract

Section: Dislcussionunclassified

Einflu� der Gewichtsreduktion auf Metabolite des Kohlenhydrat- und Fettstoffwechsels und auf das Verhalten des Seruminsulins bei Adipositas

et al. 1968

View full text Add to dashboard Cite

show abstract

Untersuchungen �ber den Fettstoffwechsel bei der Fettsucht

et al. 1966

View full text Add to dashboard Cite

Serum levels of non-esterified fatty acids, free glycerol and esterified fatty acids were estimated in obese patients and in persons of normal weight after intravenous administration of tolbutamide and glucose. In obesity non-esterified fatty acids and glycerol levels were roughly twice as high as in the non-obese, whereas no difference in levels of esterified fatty acids was found between the two groups. Following administration of tolbutamide or glucose, there was a decrease of concentration of non-esterified fatty acids and glycerol to a minimum during the two hours of observation. In obesity, non-esterified fatty acids and glycerol decreased relatively more than in persons of normal weight. This behaviour is interpreted as due to increased insulin secretion in obesity. The difference in changes in concentration of non-esterified fatty acids and glyoerol in response to a variety of test situations may well be the result of both the glucose-dependent lipogenetic and the glucose-independent antilipolytic effect of insulin. The antilipolytic effect of insulin is discussed with reference to the metabolic aspects of obesity.

show abstract

Über das Verhalten der unveresterten Fettsäuren und des Glycerins im Hungerzustand, nach Glucose- und Fructosegaben

Cited by 2 publications

References 10 publications

Einflu� der Gewichtsreduktion auf Metabolite des Kohlenhydrat- und Fettstoffwechsels und auf das Verhalten des Seruminsulins bei Adipositas

Einflu� der Gewichtsreduktion auf Metabolite des Kohlenhydrat- und Fettstoffwechsels und auf das Verhalten des Seruminsulins bei Adipositas

Untersuchungen �ber den Fettstoffwechsel bei der Fettsucht

Contact Info

Product

Resources

About