Two Flavan Derivatives Isolated from Artocarpus dadah Grown in Lampung, Indonesia

Abstract

From the root bark of Artocarpus dadah grown in Lampung, Indonesia have successfully been isolated two flavan derivatives, afzelecin-3-O-α-L-ramnoside and chatecin. The structure of both compounds were determined based on physical properties and UV-VIS, IR and NMR spectroscopies.

Cycloartobiloxanthone, a Flavonoid with Antidiabetic, Antibacterial and Anticancer Activities from Artocarpus kemando Miq.

“…Meanwhile, a reaction between the phenolic group in ring B and the NaOAc shear reagent results in the bathochromic shift in band I [35]. The findings in Table 1 reveal that Compounds 1 and 2 have similar characteristics with cycloartobiloxanthone isolated from the plant A. dadah [36]. Because the isolated compounds contain the identical peaks at the UV-Vis wavelengths, it is assumed that Compounds 1 and 2 are cycloartobiloxanthone compounds.…”

“…Both samples indicate the same substance if their IR spectra in the fingerprint region match each other [39]. Other conventional cycloartobiloxanthone compounds exhibit very identical absorption bands in the fingerprint areas of 1352, 1265, 1153, 960, and 810 cm -1 [36], suggesting that the two compounds are identical. Based on the results of characterizations of isolated compounds using UV-Vis and IR techniques as well as comparisons with standard compounds, it is then reasonable to conclude that the isolated compounds obtained from the stem wood (Compound 1) and root bark (Compound 2) of the Pudau plant (A. kemando Miq.)…”

Artonin O, a Xanthone Compound from Root Wood of Artocarpus Rigida

“…Some organic compounds have successfully been isolated from some parts of A. rigida obtained from Keputran Village, Sukoharjo, Pringsewu Lampung Indonesia. From its root bark, artonin E has been isolated and it has been shown to have good anticancer and antimalaria activities 2 .…”