Two‐dimensional π‐conjugated metal‐organic framework with high electrical conductivity for electrochemical sensing

Abstract

A two-dimensional π-conjugated metal-organic framework (MOF) with long-range delocalized electrons has been prepared and applied as modified electrode material without further post-modification. The MOF (Cu 3 (HHTP) 2 ) is composed of Cu(II) centers and a redox-active linker (2,3,6,7,10, HHTP). Compared to most MOFs, Cu 3 (HHTP) 2 displays higher electrical conductivity and charge storage capacity owing to the collective effect of metal ions and aromatic ligands with π-π conjugation. In order to confirm the superior properties of this material, the electrochemical detection of dopamine (DA) was conducted and the satisfactory results were obtained. The currents increase linearly with the concentration of DA in the range 5.0 × 10 −8 to 2.0 × 10 −4 M with a detection limit of 5.1 nM. Furthermore, Cu 3 (HHTP) 2 presents high selectivity and applicability in serum samples for electrochemical DA sensing. Overall, this material has excellent potential as a promising platform for establishing an MOF-based electrochemical sensor. K E Y W O R D S electrical conductivity, electrochemistry, metal-organic frameworks, twodimensional π-conjugated

Employing Conductive Metal–Organic Frameworks for Voltammetric Detection of Neurochemicals

“…58,59 Despite the wide range of applications of this class of materials in chemiresistive sensing of gases, 60−65 ion-to-electron transduction in potentiometry, 66 energy storage, 67−69 catalysis, 70−77 and electrochemically driven reversible gas capture, 77 the use of conductive MOFs as active components in voltammetric detection of multianalyte systems has been limited. 78 To this day, MOFs have been primarily used as colorimetric and luminescence sensors, 79−83 scaffolds, 84−86 and carriers 87,88 in biosensors rather than the electroactive materials due to limited conductivity and stability in aqueous solutions. 89 Recently, the ability to achieve conductivity in 3D MOFs, through doping or mixing with conductive materials such as carbon or metal nanoparticles, has enabled the implementation of these composite materials in the detection of glucose, 87 L-cystine, 90 and dopamine.…”

Two-dimensional conjugated metal–organic frameworks (2D c-MOFs): chemistry and function for MOFtronics

“…53 Regardless of the preliminary success, the study towards complicated reactions such as CO 2 RR is still at infancy, and in-depth investigation on the mechanisms remains of growing interest. In the past few years, 2D c-MOFs stand out for electrochemical molecular capture 109 and detection 239,240 as well.…”

Conductive Metal–Organic Frameworks: Design, Synthesis, and Applications

“…[ 112 ] Similarly, conductive MOFs could also be obtained in this way following different design principles. [ 33,44,108 ] Also, the structures and properties of MOFs can be flexibly modified by physical or chemical methods for different applications, which is suitable for exploring and expanding the conductivity and application of MOFs. Through postsynthesis modification strategies, many redox‐active molecules, clusters, and even polymers can be integrated with MOFs to construct MOFs composites, rendering MOFs with good conductivity and broad applications.…”

“…[ 29,32 ] Their defined porous structures, tailored morphologies, and pore sizes as well as large surface area endow them with various applications. [ 44 ] However, their further applications may be restricted due to their limited conductivity and structure stability. Considering their modifiable structures and properties, these disadvantages can be artificially overcome by further structure design.…”