Two Cases of Desmoplastic Trichoepithelioma

Matsuki, Takahiro; Hayashi, Nobuyuki; Mizushima, Junichi; Igarashi, Atsuyuki; Kawashima, Makoto; Harada, Shinji

doi:10.1111/j.1346-8138.2004.tb00608.x

Cited by 6 publications

(4 citation statements)

References 4 publications

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“…Two malignant tumours were reported in our study. The present study shows nodular hidradenoma as the predominant tumour similar to Radhika K et al, 5 and trichoepithelioma 6 is the next common tumour. Trichoepitheliomas were the most common tumours in other studies.…”

Section: Discussionsupporting

confidence: 88%

A clinico-histopathological study of skin appendageal tumours in a tertiary health care centre in western Odisha– A case series

Mishra,

Sahu,

Panigrahi

et al. 2023

ACHR

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Skin appendageal tumours (SATs) are those neoplasms that arise from pilosebaceous, apocrine, or eccrine sweat glands. These are a diverse group of tumours with both benign and malignant counterparts. They can be single, multiple, or have a syndromic association with internal malignancies. Benign adnexal tumours are more common, while malignant adnexal tumours are rare, usually locally aggressive, and have the potential for nodal involvement and distant metastasis with a poor clinical outcome. Therefore, proper diagnosis of SATs is important for therapeutic and prognostic reasons.This study aims to determine the clinico-histopathological correlation in cases of SATs in our hospital. It is a case series conducted over a one-and-a-half year period from January 2021 to July 2022. All clinically suspected cases of SATs were examined, biopsied, and subjected to histopathological examination. Histopathologically confirmed cases of SATs were finally analysed. Among twenty-four thousand two hundred twenty-four new patients attending OPD, 30 suspected cases of ATs underwent histopathological examination. Histopathology was confirmatory in only 12 cases (40%). 10 cases were benign, and two were malignant. Out of 10 benign cases, hidradenoma was noted in 3 (25%), trichoepithelioma in 2 (16%), proliferating pilar tumour, apocrine hidrocystoma, steatocystoma multiplex, hidradenoma papilliferum, and pilomatrixoma were seen in one each. Females (75%) outnumbered males (25%) in our study population.: SATs are infrequent and are not frequently observed in the field of surgical pathology. Histopathology is the gold standard for diagnosis.

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Section: Discussionsupporting

confidence: 88%

A clinico-histopathological study of skin appendageal tumours in a tertiary health care centre in western Odisha– A case series

Mishra,

Sahu,

Panigrahi

et al. 2023

ACHR

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“…Clinically, however, this benign neoplasm is typically easier to differentiate from a microcystic adnexal carcinoma than is sclerosing basal cell carcinoma. The stereotypical presentation of a desmoplastic trichoepithelioma consists of a small solitary plaque with a central depressed area and elevated borders, 22 in contrast to the larger, firm, pale to yellow plaque or nodule with an average size at presentation of 2 cm in the case of a microcystic adnexal carcinoma 23 . Swanson et al 24 also reported that the majority but not all of their cases of classical and desmoplastic trichoepitheliomas were positive on staining with Ber‐EP4.…”

Section: Discussionmentioning

confidence: 99%

Monoclonal antibody Ber‐EP4 reliably discriminates between microcystic adnexal carcinoma and basal cell carcinoma

Krahl

Sellheyer

2007

J Cutan Pathol

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“…35 Desmoplastic trichoepithelioma (DTE) variant occurs most commonly on the faces of young females. Histologically, it is characterised by narrow, compressed strands of basaloid germinative epithelium, with or without small horn cysts, embedded in densely sclerotic stroma within the upper dermis 36 (fig 6A-C). It is important to differentiate DTE from morphoealike BCC.…”

Section: Tumours Of Hair Follicle (Pilar) Originmentioning

confidence: 99%

Skin adnexal neoplasms—part 1: An approach to tumours of the pilosebaceous unit

Alsaad

Obaidat²,

Ghazarian³

2006

J Clin Pathol

176

208

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Skin adnexal neoplasms comprise a wide spectrum of benign and malignant tumours that exhibit morphological differentiation towards one or more types of adnexal structures found in normal skin. Most adnexal neoplasms are relatively uncommonly encountered in routine practice, and pathologists can recognise a limited number of frequently encountered tumours. In this review, the first of two, the normal histology of the skin adnexal structures is reviewed, and the histological features of selected but important benign and malignant tumours and tumour-like lesions of pilosebaceous origin discussed, with emphasis on the diagnostic approach and pitfalls in histological diagnosis.

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Two Cases of Desmoplastic Trichoepithelioma

Cited by 6 publications

References 4 publications

A clinico-histopathological study of skin appendageal tumours in a tertiary health care centre in western Odisha– A case series

A clinico-histopathological study of skin appendageal tumours in a tertiary health care centre in western Odisha– A case series

Monoclonal antibody Ber‐EP4 reliably discriminates between microcystic adnexal carcinoma and basal cell carcinoma

Skin adnexal neoplasms—part 1: An approach to tumours of the pilosebaceous unit

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