“…In 2 articles relevant to this issue [26,27], a linkage was suggested between FCHL and the locus 1q21-23 including the TNF superfamily member-1B. Reduced plasma levels of soluble-TNF-receptor p75, 1 of the 2 binding domains of the TNF-α receptor, were found in patients with FCHL [26], thus suggesting an increased number of TNF-α receptors bound to target cells.…”