Tumeur de Buschke- Lowenstein à localisation anorectale

Qarro, A.; Ali, Abdelmounaim Ait; Choho, A.; Alkandry, S.; Borki, K.

doi:10.1016/j.anchir.2004.06.005

Cited by 22 publications

(34 citation statements)

References 10 publications

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“…Lymph node dissection is not recommended because of low nodal involvement rate and the low metastatic potential of BLT [7] . None of the patients who underwent an APE had lymph node involvement.…”

Section: Discussionmentioning

confidence: 99%

“…The main difficulty is to assess the ideal resection extension to both achieve a complete resection and remain as conservative as possible [8,12] . When the anal sphincter, anal canal, lower rectum or upper rectum is invaded, an APE of the rectum is indicated, as in 4 of our patients who had local recurrence invading the rectum [2,3,7] . Decision between local excision and APE will be mainly based on endoanal US.…”

Section: Discussionmentioning

confidence: 99%

“…Its diagnosis is often delayed, even after several years of local treatment [2,8,15] . The prognosis of these tumors is conditioned by the incidence of local recurrence (60-70%) and the risk of malignant transformation (30-50%) [2,7,8,12,13] . To our knowledge, predictive factors of malignant transformation have not been identified in previously published observations and cohorts.…”

Section: Discussionmentioning

confidence: 99%

“…Histological examination of BLT shows a benign appearance as it is a pseudo-epitheliomatous proliferation characterized by exo-and endophytic hyperpapillomatosis with epithelial hyperplasia, hyperacanthosis and koilocytosis; transition toward squamous epithelial cancer does not appear with distinctive pathological characteristics [1,3,4,7,9,12,15] . Moreover, those tumors behave malignantly by destroying adjacent tissues.…”

Section: Introductionmentioning

confidence: 99%

“…Environmental risk factors are essentially linked to HPV contamination risk factors: young age, high number of sexual partners, unpro-tected intercourse and anal intercourse [7-10, 12, 15, 16] . Its evolution toward squamous cell carcinoma (SCC) has been previously described, the diagnosis of which is made on deep biopsies or surgical specimens [1,7,8] . Usually, these lesions are not associated with metastasis [1, 7-9, 12, 13, 16] .…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Should the Surgical Management of Buschke-Lowenstein Tumors Be Aggressive? About 10 Cases

Fanget

Pasquer²,

Djeudji³

et al. 2016

Dig Surg

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Aims: Buschke-Lowenstein tumor (BLT) of the anal margin is a histologically benign tumor whose degeneration can lead to a deadly local evolution because of difficult and late diagnosis. The objective of this study was to report our experience and propose a therapeutic strategy for these rare tumors. Methods: From 1996 to 2014, 10 men with a median age of 45 years (25-64) were treated for a BLT of the anal margin with a first local excision possibly followed by rectal amputation. Results: Local perianal excision was curative in 6 cases without recurrence. The median follow-up time was 94.5 months (5-175). In 4 patients, local excision was followed by an early recurrence, justifying a complementary abdominoperineal excision (APE) of the rectum. Two patients who benefited from complementary resection are currently free from recurrence. Even if the postoperative course was uneventful, 2 died from recurrence and disease progression within 5 and 11 postoperative months each. Conclusion: Macroscopic surgical evaluation of local tumoral invasion and extensive radical resection appears to be associated with long-term survival without recurrence. When recurrence occurs, APE of the rectum seems to be the only curative alternative. Based on low level of evidence, surgical excision is currently the only standard treatment for these lesions.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Should the Surgical Management of Buschke-Lowenstein Tumors Be Aggressive? About 10 Cases

Fanget

Pasquer²,

Djeudji³

et al. 2016

Dig Surg

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Une formation géante périanale

et al. 2013

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La tumeur de Buschke-Löwenstein à localisation anorectale: à propos de deux cas

Hiroual

Zougarhi

Idrissi

et al. 2009

J Afr Hepato Gastroenterol

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La tumeur de Buschke-Löwenstein ou condylome acuminé géant est une prolifération d'aspect pseudoépitheliomateux dont l'évolution se fait vers l'extension en surface et en profondeur, avec le risque de dégénérescence maligne. Nous rapportons deux observations de volumineuses tumeurs de Buschke-Löwenstein à localisation anorectale confirmées histologiquement. L'imagerie en coupe est capitale pour le bilan de résécabilité permettant d'évaluer le degré de vascularisation et d'extension locale. La chirurgie est le traitement de référence pouvant aller de la simple résection jusqu'à l'amputation large mutilante. Mots clés Tumeur de Buschke-Löwenstein · Condylome accuminé · Papilloma virusAbstract Buschke-Löwenstein tumor or giant condyloma acuminata is characterized by a proliferation locally aggressive with extensive tissue destruction. We report two cases of Buschke-Löwenstein tumor with anorectal localization confirmed by histology. The imagery is capital for the assessment of resecability; it allows evaluating the degree of vascularization and local extension. The surgery is the treatment of reference, which can go from the simple resection until the mutilating broad amputation.

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Tumeur de Buschke- Lowenstein à localisation anorectale

Cited by 22 publications

References 10 publications

Should the Surgical Management of Buschke-Lowenstein Tumors Be Aggressive? About 10 Cases

Should the Surgical Management of Buschke-Lowenstein Tumors Be Aggressive? About 10 Cases

Une formation géante périanale

La tumeur de Buschke-Löwenstein à localisation anorectale: à propos de deux cas

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