Triterpene saponins from Fagonia scabra Forssk and other Fagonia species

Boutaghane, Naima; Kabouche, Zahia; Voutquenne-Nazabadioko, Laurence

doi:10.1016/j.bse.2016.05.017

Cited by 1 publication

(6 citation statements)

References 28 publications

(46 reference statements)

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“…F. indica Flavonoids [37] , Triterpenoid Saponins [37,39] , steroidal saponin glycoside [40] , (indicasaponin A) and (indicasaponin B) [41] , and Taraxast-20-en-28-oic acid Saponins [42] . F. Sinaica Boiss flavonol glycosides [43,44] .…”

Section: Phytochemistrymentioning

confidence: 99%

“…Flavonol glycosides [39,45] and Triterpene Saponins [39] . F. Tenuifolia Steud Flavonol glycosides [43] .…”

Section: F Microphyllamentioning

confidence: 99%

“…Melek et al, [30] have previously studied F.cretica for its saponin content to isolate and identify three bisdesmosides of oleanolic acid and Hederagenin. Moreover 3-O-β-Dglucopyranosyl-Hederagenin (10) was isolated from the aerial part of F.cretica [39] . The isolation of a new Triterpene glycoside;3-β-O-[(6-deoxyα-L-talopyranosyl)oxy]-22-α-hydroxyurs-12-en-28-oic acid (fagonoside A) (11) from the whole plant of F. cretica has been recognized by Anjum et al [50] .…”

Section: Saponinsmentioning

confidence: 99%

“…Ursane Triterpenoid type of saponin such as ursolic acid was isolated from F. indica, carbonyl in C-28 position was glycosylated by a b-D-glucopyranosyl unit. The hydroxyl in C-3 position was also glycosylated by a sulfated Larabinopyranosyl which can be substituted in C-2 position by a b-D-xylopyranosyl units, these compounds known as indicasaponin C ( 16) and indicasaponin D(17) [39] . A noval steroidal saponin was isolated from F. indica, which recognized as: 12-(4-methyl-pent 3enoyloxy)-20-(4-methylpent-3-enoyloxy)-3β,12β,20 β-trihydroxypregnane-3-ylO-β-D-cymapyranosyl-(1 → 4)-3-methoxy-6-deoxy-β-Dglucopyranoside (18) [40] .…”

Section: Saponinsmentioning

confidence: 99%

“…Concerning F. glutinosa, Melek et al [47] isolated and determined twelve Triterpenoid Saponins from the aerial parts extracts of this species. Six of which are new, and were identified as [39] .…”

Section: Saponinsmentioning

confidence: 99%

See 4 more Smart Citations

The species of genus fagonia in Libya: (A comprehensive review)

Alamami¹,

Elshibani²,

Elremali³

et al. 2022

J Pharmacogn Phytochem

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The Plants of the genus Fagonia have been broadly utilized as adjunctive therapy, to treat several conditions involving high fever, diabetes, asthma, stoma chache, dental pain, and renal problems using their aqueous extracts as medicines. This genus is a valuable source that comprises a variety of Triterpenes, flavonoids, and Saponins. The herbal chemistry as well as the biological action of Fagonia species have been a candidate for many researchers. The in vivo pharmacological screening of their extracts has manifested some other significant properties such as cytotoxic and anti-cancer activity. This review study has gathered the important research that has been carried out on the species that grow in Libya. It includes an exhaustive survey of literature about the medicinal value and the bioactivities of various extracts obtained from these Fagonia species using references from major databases.

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