Trimodal synergistic antitumor drug delivery system based on graphene oxide

Zhang, Xuwu; Luo, Liyao; Li, Lei; He, Yuchu; Cao, Weiwei; Liu, Huan; Niu, Kang; Gao, Dawei

doi:10.1016/j.nano.2018.09.008

Cited by 58 publications

(28 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…MTT is commonly used method to evaluate the cytotoxicity of nanoparticles. [47][48][49] As illustrated in Fig. 8, the cell viability was higher than 90% aer incubation with Pd n -LNT NPs and LNT at a concentration within 1000 mg mL À1 .…”

Section: Biocompatibilitymentioning

confidence: 89%

Green synthesis of palladium nanoparticles using lentinan for catalytic activity and biological applications

et al. 2019

View full text Add to dashboard Cite

show abstract

Section: Biocompatibilitymentioning

confidence: 89%

Green synthesis of palladium nanoparticles using lentinan for catalytic activity and biological applications

et al. 2019

View full text Add to dashboard Cite

show abstract

“…It has been shown that after treatment for 14 days with ICG-Wed-GO and NIR, cancer cells were completely lost in tumor-bearing mice. Furthermore, the insignificant ICG-Wed-GO toxic effect has been established [139]. The ability of GO to change its fluorescence at visible/NIR wavelengths as a function of pH was applied to scan cancerous tissues.…”

Section: Drug Delivery Systemsmentioning

confidence: 99%

Graphenic Materials for Biomedical Applications

Plachá

Jampílek

2019

Nanomaterials

View full text Add to dashboard Cite

Graphene-based nanomaterials have been intensively studied for their properties, modifications, and application potential. Biomedical applications are one of the main directions of research in this field. This review summarizes the research results which were obtained in the last two years (2017-2019), especially those related to drug/gene/protein delivery systems and materials with antimicrobial properties. Due to the large number of studies in the area of carbon nanomaterials, attention here is focused only on 2D structures, i.e. graphene, graphene oxide, and reduced graphene oxide.

show abstract

“…On the base of GO for NIR light controlling chemotherapeutic/photodynamic (PDT)/photothermal (PTT) trimodal synergistic therapy, a multifunctional antitumor drug delivery system was synthesized. Indocyanine green-wedelolactone-GO could effectively absorb and transform optical energy to heat under NIR laser irradiation, generate damage and ablate tumor cells by reactive oxygen species [ 151 ]. Fan, Jing et al [ 152 ] reported the novel sandwich nanomedicine with NIR light responsive release of nitric oxide (NO) has been constructed by a NO donor BNN6 (N,N′-di- sec -butylN,N′-dinitroso-1,4-phenylenediamine) through self-assembly of GO nanosheets.…”

Section: Classification Of Stimuli Responsive Two-dimensional Materiamentioning

confidence: 99%

Recent advances of two-dimensional materials in smart drug delivery nano-systems

Zhang

Fan

Chen

et al. 2020

Bioactive Materials

132

View full text Add to dashboard Cite

Smart drug delivery nano-systems show significant changes in their physical or chemical properties in response to slight change in environmental physical and/or chemical signals, and further releasing drugs adjusted to the progression of the disease at the right target and rate intelligently. Two-dimensional materials possess dramatic status extend all over various scientific and technological disciplines by reason of their exceptional unique properties in application of smart drug delivery nano-systems. In this review, we summarized current progress to highlight various kinds of two-dimensional materials drug carriers which are widely explored in smart drug delivery systems as well as classification of stimuli responsive two-dimensional materials and the advantages and disadvantages of their applications. Consequently, we anticipate that this review might inspire the development of new two-dimensional materials with smart drug delivery systems, and deepen researchers’ understanding of smart nano-carries based on two-dimensional materials.

show abstract

Trimodal synergistic antitumor drug delivery system based on graphene oxide

Cited by 58 publications

References 41 publications

Green synthesis of palladium nanoparticles using lentinan for catalytic activity and biological applications

Green synthesis of palladium nanoparticles using lentinan for catalytic activity and biological applications

Graphenic Materials for Biomedical Applications

Recent advances of two-dimensional materials in smart drug delivery nano-systems

Contact Info

Product

Resources

About