Trends of Colorectal Cancer Incidence in Kazakhstan

Mauyenova, Dana; Zhadykova, Yerkezhan; Khozhayev, Arman; Turebayev, Dulat; Kulmirzayeva, Dariyana; Urazova, Saltanat; Nurtazinova, Gaukhar; Kuandykov, Yerlan; Amanshayeva, Akmaral; Sakhanov, Sauirbay; Bukeyeva, Zhanar; Openko, Vladimir; Orazbayev, Serikbay; Kozhakhmetov, Saken; Bilyalova, Zarina; Igissinova, Gulnur; Jarrahi, Alireza Alireza Mosavi; Igissinov, Nurbek

doi:10.31557/apjcp.2021.22.10.3405

Cited by 3 publications

(4 citation statements)

References 42 publications

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“…As stated in the results of a cross-sectional study carried in the northern part of Iran, it's expected that CRC will have an increasing trend, which may be related to the level of detection of CRC, as well with early diagnosis, treatment and its cost (Janbabaee et al, 2021). Taking into account the results of recent studies on the incidence of CRC in Kazakhstan (Mauyenova et al, 2021), where there is an increase in the incidence, we can also expect that in the future the incidence and mortality rates will decrease.…”

Section: Discussionmentioning

confidence: 99%

Colorectal Cancer Mortality in Kazakhstan: Spatio-Temporal Epidemiological Assessment

Mauyenova

AXARIN

Telmanova

et al. 2022

Asian Pac J Cancer Prev

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Objective: The aim is to study the trends in colorectal cancer (CRC) mortality in Kazakhstan. Methods: The retrospective study was done using descriptive and analytical methods of oncoepidemiology. The extensive, crude and age-specific mortality rates are determined according to the generally accepted methodology used in sanitary statistics. Results: CRC mortality in Kazakhstan is considered to be increasing. Therefore, this study (for the period 2009-2018) was undertaken to retrospectively evaluate data across the country available from the central registration bureau. Age standardized data for mortality was generated and compared across age groups. It was determined that during the studied period 15,200 died of this pathology. During the studied years an average age of the dead made 69.8 years (95%CI=69.5-70.0). The average annual standardized mortality rate was 10.2 per 100,000, and in dynamics tended to decrease. Peak of mortality was noted in aged 60-84 years. Trends in age-related mortality rates had a pronounced tendency to increase in 30-34 years (T=+11.7%, R 2 =0.7980) and to decrease in 75-79 years (T=–16.4%, R 2 =0.8881). In many regions, there is a decrease in the number of deaths. During the compilation of cartograms, mortality rates were determined on the basis of standardized indicators: low – up to 8.9, average – from 8.9 to 11.5, high – above 11.5 per 100,000 for the entire population. In addition, all calculations were made taking into account age-sex differences. Conclusion: Trends in mortality from CRC in recent years have decreased from 11.2 to 7.7 per 100,000 of the total population, while the trend is stable (T=−3.6%, R 2 =0.8745). The study of regional mortality has theoretical and practical significance: monitoring and evaluation of the effectiveness of early detection and treatment of detected pathology. Health authorities should take into account the results obtained when organizing anti-cancer measures.

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Section: Discussionmentioning

confidence: 99%

Colorectal Cancer Mortality in Kazakhstan: Spatio-Temporal Epidemiological Assessment

Mauyenova

AXARIN

Telmanova

et al. 2022

Asian Pac J Cancer Prev

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“…In 2021 in Kazakhstan, CC exhibited a crude incidence rate of 18.3 cases per 100 000 women and a crude mortality rate of 9.1 per 100 000 women 11. Over the period from 2009 to 2018, there was a trend of increase in the overall incidence of CC in the Republic of Kazakhstan, as well as in all its regions 12…”

Section: Introductionmentioning

confidence: 99%

“…11 Over the period from 2009 to 2018, there was a trend of increase in the overall incidence of CC in the Republic of Kazakhstan, as well as in all its regions. 12 …”

Section: Introductionmentioning

confidence: 99%

Exploring HPV vaccine knowledge, attitudes, barriers and information sources among parents, health professionals and teachers in Kazakhstan: a mixed-methods study protocol

Kassymbekova,

Zhetpisbayeva,

Tcoy

et al. 2023

BMJ Open

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IntroductionHuman papillomavirus (HPV) is a prevalent sexually transmitted infection linked to certain types of malignant neoplasms, notably cervical cancer (CC). In Kazakhstan, a high prevalence of high oncogenic HPV types (HR-HPV) has been observed, and CC ranks as the second most common malignancy among women with a crude incidence rate of 18.3 cases per 100 000 women. The HPV vaccine, developed as the primary prevention measure against HPV infection, including the most prevalent HR-HPV, received approval from the WHO in 2009. In 2014, Kazakhstan initiated HPV vaccination as a pilot project in four sub-national regions; however, it was later in 2017 discontinued due to widespread parental refusal influenced by negative media reports. This study aims to examine knowledge, attitudes, information sources, barriers to HPV vaccination and factors associated with HPV vaccination hesitancy among different target groups in Kazakhstan prior to the HPV vaccine re-launch announced by the Ministry of Health.Methods and analysisThis mixed-method-designed research comprises quantitative and qualitative components. Data on HPV awareness, attitudes towards HPV vaccination and sources of information will be collected through an online survey administered by parents and legal guardians, health professionals, and schoolteachers in the Republic of Kazakhstan between January 2023 and January 2024. Additionally, qualitative data on Kazakhstani parental beliefs and attitudes toward HPV vaccination will be collected through online focus group discussions.Ethics and dissemination of resultsThe study has been approved by the local ethics committee at the Kazakhstan Medical University “Higher School of Public Health” (KMU “KSPH”) (No. 138 of 31.05.2021). The results will be reported in publications, at conferences among researchers and healthcare and school education professionals in Kazakhstan, and internationally.

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“…In a recent study on CRC incidence in Kazakhstan, it was found that the incidence is 16.9 per 100,000 population and tends to increase [10]. Therefore, there is an interest in studying each section of the large intestine separately.…”

Section: Introductionmentioning

confidence: 99%

The Impact of Covid-19 on the Incidence of Rectal Cancer in Kazakhstan: Results of Component Analysis

Telmanova

AXARIN

ORALBEK

et al. 2022

Onkol. radiol. Kaz.

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Relevance: Every year, 732,210 new cases of RC are registered globally, with an incidence of 7.6 per 100,000. The COVID-19 pandemic has affected the screening, case detection, and referral of patients with an asymptomatic cancer diagnosis. The aim was to assess the trends in rectal cancer incidence in the entire population of Kazakhstan before and during the COVID pandemics. Methods: The data obtained from the Ministry of Healthcare of the Republic of Kazakhstan concerning RC (Form no. 7) was retrospectively studied by descriptive and analytical epidemiology methods. The component method was used to analyze RC incidence dynamics based on the number of cases from 2010 to 2020. Results: From 2010 to 2020, the risk of getting RC went down. An increase in incidence in 2010-2020 (+24.8%) was lower than in the preCOVID period of 2010-2019 (+37.2%). We found a sharp decrease in RC incidence from 2019 to 2020. The overall decrease was 0.89‰⁰⁰ due to changes in the age structure of the population (∑ΔA=+0.13‰⁰⁰), the risk of getting RC (∑ΔR=−1.02‰⁰⁰), and the combined impact of age structure and the risk of getting RC (∑ΔAR=−0.002‰⁰⁰). According to the component analysis, 1,662 patients with RC were expected in 2020; instead, only 1,471 cases were registered. Such a decline in cases was mainly due to a reduced risk of getting RC. Conclusions: The analysis of RC incidence trends in Kazakhstan shows a negative impact of COVID-19 on cancer care indicators and effectiveness. All oncological examinations were strengthened with the resumption of work after COVID restrictions. However, the number of screening visits remains lower than in previous years. Untimely diagnosis can increase the number of cases of late-stage CRC and an overall loss of years of life due to the lack of proper treatment. However, these forecasts can be mitigated by proper follow-up.

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Trends of Colorectal Cancer Incidence in Kazakhstan

Cited by 3 publications

References 42 publications

Colorectal Cancer Mortality in Kazakhstan: Spatio-Temporal Epidemiological Assessment

Colorectal Cancer Mortality in Kazakhstan: Spatio-Temporal Epidemiological Assessment

Exploring HPV vaccine knowledge, attitudes, barriers and information sources among parents, health professionals and teachers in Kazakhstan: a mixed-methods study protocol

The Impact of Covid-19 on the Incidence of Rectal Cancer in Kazakhstan: Results of Component Analysis

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