Trends in mortality from lupus in Spain from 1980 to 2018

Hernández‐Rodríguez, Juan‐Carlos; Durán‐Romero, Antonio José; Jiménez, A. Muñoz; Conejo‐Mir, Julián; Pereyra‐Rodriguez, José Juan

doi:10.1177/0961203320952864

Cited by 5 publications

(4 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Bartels et al 22 demonstrated 10-year mortality rate of 26% in SLE compared with 19% for age-matched comparators (hazards ratio [HR], 2.1; p < 0.01) and increased HR of CVD event or death (HR, 1.8; p = 0.01). This finding was further supported by the recently published article by Hernandez-Rodriguez et al, 23 which examined death records and mid-year population in Spain from 1980 to 2018. They also found the overall SLE mortality rates increased in Spain from 0.83 per 1,000,000 in 1980 to 1984 compared with 1.77 per 1,000,000 from 2014 to 2018.…”

Section: Discussionsupporting

confidence: 62%

Proportionate Cardiovascular Mortality in Chronic Inflammatory Disease in Adults in the United States From 1999 to 2019

Shah¹,

Wass

Hajjari

et al. 2022

J Clin Rheumatol

View full text Add to dashboard Cite

Background: Despite a rising prevalence of chronic inflammatory disease (CID), the recent trends in cardiovascular disease (CVD) mortality of patients with CID is scarce. In this study, we investigated patterns of CVD mortality in systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), and rheumatoid arthritis (RA) compared with the general population.Methods: We used the 1999 to 2019 multiple causes of death files from the national center for health statistics to analyze patterns and trends of proportionate CVD mortality in CID compared with the general population. Results:We analyzed a total of 11,154 CVD deaths in IBD, 58,337 CVD deaths in RA, 6227 CVD deaths in SLE, and 17,826,871 CVD deaths in the general population. Between 1999 and 2019, we found that proportionate CVD mortality decreased significantly in the IBD group (25% to 16%), RA group (34% to 25%), and the general population (41% to 31%), but did not change for the SLE group (15% to 15%). Patients with SLE who died of CVD were approximately 10 years younger compared with CVD decedents with RA, IBD, or general population. The White population had higher proportionate CVD mortality than African American (IBD [19% vs 16%-18%] and SLE [14%-16% vs 12-14%], respectively).Conclusions: This study identifies current trends in CVD mortality in the CID population and elucidates current demographics in CVD mortality in CID. Although proportionate CVD mortality decreased in the general population, and in patients with RA and IBD, there was no change among patients with SLE. Further studies are needed to elucidate these differences.

show abstract

Section: Discussionsupporting

confidence: 62%

Proportionate Cardiovascular Mortality in Chronic Inflammatory Disease in Adults in the United States From 1999 to 2019

Shah¹,

Wass

Hajjari

et al. 2022

J Clin Rheumatol

View full text Add to dashboard Cite

show abstract

“…The number of participants was small and, consequently, the more under-represented opinions may have been overlooked, without achieving sufficient significance to be identified. However, there is no agreement on the panel size for Delphi studies and panels with “small” size also provide reliable criteria when they include highly trained experts (Akins et al ., 2005; Keeney et al ., 2001). Nevertheless, expert participants came from across Spain, from different settings and services, which conferred high representativeness.…”

Section: Limitationsmentioning

confidence: 99%

“…In Spain, SLE is one of the most frequent autoimmune diseases, with a prevalence of 210/100,000 inhabitants (Cortés Verdú et al, 2020;Seoane-Mato et al, 2018). Prognosis of SLE has significantly improved recently (Hernández-Rodríguez et al, 2020); however, people with SLE have a mortality risk two to three times higher than the general population (Bernatsky et al, 2006). Prompt diagnosis, accurate treatment, and close follow-up are key to prevent rapid disease progression and minimize the accumulation of organ damage (Mcelhone et al, 2006) and survival (Bernatsky et al, 2006;Bruce et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Nursing Recommendations in the Management of Systemic Lupus Erythematosus: A Delphi Consensus

García

Quesada

Vargas

et al. 2023

Hisp Health Care Int

View full text Add to dashboard Cite

Introduction: Nurses’ role in the management of people with systemic lupus erythematosus (SLE) is essential. Specific guidelines for nurses have not been previously developed in Spain. This project aimed to try to develop comprehensive and validated recommendations for nurses regarding the management of people with SLE. Method: A Delphi questionnaire with 90 general and specific recommendations was designed by the scientific committee and underwent two rounds of participation. Results: Panellists reached a consensus on “agreement” for 85 recommendations during the first round and for 87 recommendations after the second and final rounds. Panellists agreed that people with SLE should be managed within a multidisciplinary team, and that this team should include specialized nurses. Panellists stated that most of the services lack specialized nurses. Experts identified lack of specific training programs targeted to nurses as the main barrier for application of recommendations. Panellists recommended an extended role for nurses in the management of people with SLE, including diagnosis, patient education, treatment monitoring and administration, and follow-up. Conclusions: This study is the first consensus that provides nursing recommendations from experts on the management of people with SLE in Europe. Design of standardized training programs targeted to nurses would facilitate the application of the recommendations.

show abstract

“…9 Previous epidemiological studies with standardised methodologies have examined the SLE mortality rates in Spain over large periods of time. 10,11 These studies showed that overall age-standardised mortality rates (ASMRs) due to SLE increased from 1980 to 1999 and remained stable until 2018.…”

Section: Introductionmentioning

confidence: 99%

Clustering of systemic lupus erythematosus mortality in southwestern Spain

Cayuela,

Pereyra-Rodríguez,

Hernández-Rodríguez

et al. 2023

Lupus

Self Cite

View full text Add to dashboard Cite

Objective To analyse time trends in systemic lupus erythematosus (SLE) mortality and explore possible provincial clustering of SLE mortality in Spain (2001–2020). Methods We conducted an ecological study using deaths registered in SLE at the Spanish National Institute of Statistics between 2001 and 2020. Jointpoint regression models have been used to evaluate temporal trends. To analyse the spatial pattern of SLE mortality in men and women in Spain, crude rates, age-standardised mortality rates (ASMRs), smooth relative risk (RR) and posterior probabilities (PP) for RR greater than one for the period 2001–2020 were calculated. The Global Moran I index was used to assess the existence of global spatial autocorrelation. Local indicators of spatial association (LISA) and Kulldorff’s spatial scan statistic were used to identify clusters. Results Over the 20 years analyzed in this study, the SLE average ASMR for the period was 2.7 for women and 0.7 for men, with a sex ratio (female/male) of 3.8. In men, no province showed a RR>1. Conversely, in women, eight provinces showed values of RR> 1 with a PP greater than 0.8 (Seville, Cadiz, Huelva and Murcia in the south, Barcelona, Zaragoza, Huesca and Leon in the north). In men, neither of the two methods detected a clustering of provinces. However, in women, both methods identified a cluster of provinces located in the southwest of the country (Huelva, Cádiz, Seville and Malaga) as a cluster with significant excess mortality. In the second cluster (centred on the province of Huelva) obtained with the Kulldorff method, two more provinces were added (Badajoz and Cordoba, also located in the southwest). Conclusions We detected a cluster of provinces with an excess risk of female SLE mortality in the southwest of Spain.

show abstract

Trends in mortality from lupus in Spain from 1980 to 2018

Cited by 5 publications

References 28 publications

Proportionate Cardiovascular Mortality in Chronic Inflammatory Disease in Adults in the United States From 1999 to 2019

Proportionate Cardiovascular Mortality in Chronic Inflammatory Disease in Adults in the United States From 1999 to 2019

Nursing Recommendations in the Management of Systemic Lupus Erythematosus: A Delphi Consensus

Clustering of systemic lupus erythematosus mortality in southwestern Spain

Contact Info

Product

Resources

About