Trends in Incidence and Susceptibility among Methicillin-Resistant Staphylococcus aureus Isolated from Intranasal Cultures Associated with Rhinosinusitis

Abstract

ABSTRACT

Staphylococcus aureus colonisation in patients from a primary regional hospital

“…The acquired resistance of S. aureus has been the focus of several publications, especially after penicillin began to be used in the middle of the past century, regarding MRSA epidemiology and its resistance to penicillin. Transmission mainly occurs in hospitals ( 20 – 22 ). The excessive use of antibiotics in hospitals is considered a major risk in the guidelines of the Society for Healthcare Epidemiology of America (SHEA) ( 23 ).…”

Fighting sinus‐derived Staphylococcus aureus biofilms in vitro with a bacteriophage‐derived muralytic enzyme

“…Importantly, it was found that P128 was not only effective against MSSA isolates, but also maintained efficacy when tested against an MRSA sinus‐derived clinical isolate. Rates of MRSA in CRS have been seen to be as high as 26% in 2010, with the trend of MRSA isolation increasing . Further, it has been noted that high nasal burden of MRSA is linked with an increased risk of developing invasive infection and is a reservoir for bacteraemia .…”

Epidemiology of chronic rhinosinusitis, selected risk factors, comorbidities, and economic burden

“…Currently, the incidence of Staph. aureus positive cultures amounts to 7.7% and the one of MRSA positive cultures to 1.06% [ 58 ].…”

“…aureus in 19% of the patients with CRS [ 62 ]. Among those, 19% were MRSA so that in this context the incidence of MRSA in CRS is relatively stable with 3.8% of the CRS patients in the last years [ 58 ]. However, those data are not confirmed.…”