Trehalose synthesis during differentiation in Dictyostelium discoideum. IV. Secretion of trehalase and the in vitro expression of trehalose-6-phosphate synthetase activity

Regulation of trehalose mobilization in fungi

“…Commitment to aggregation is enough to induce trehalase secretion since aggregation itself can be inhibited without preventing the secretion of trehalase (24). During formation of the fruiting bodies, trehalase activity increases again and reaches a value of between 50 and 200% of the value found in free-living myxamoebae (83,84,152). The increase in the activity is restricted completely to the stalk cells of the fruiting body.…”

“…The trehalase activity remains approximately constant in free-living myxamoebae (24). Aggregation of the vegetative myxamoebae upon starvation is associated with secretion of trehalase into the medium, which results in a drastic decrease in the intracellular activity (24,83,84,152). Commitment to aggregation is enough to induce trehalase secretion since aggregation itself can be inhibited without preventing the secretion of trehalase (24).…”