Treatment Outcome and Factors Affecting Dental Arch Relationship in Malay Children with Unilateral Cleft Lip and Palate (UCLP)

Abstract

The purpose of this study was to evaluate the dental arch relationship of non-syndromic Malay unilateral cleft lip and palate (UCLP) children and also assess the various congenital and postnatal treatment factors that affect dental arch relationship. Study models of 107 UCLP children were included in this study that was treated in Hospital Universiti Sains Malaysia over a period of 12 years (2000-2012). The mean age was 7.69± 2.46 (mean± SD). The dental arch relationship was assessed by GOSLON Yardstick which comprises five categories; named-1: excellent; 2: good; 3: fair; 4: poor; 5: very poor. All the subjects were divided into two groups; favorable (category ratings 1-3) and unfavorable (category ratings 4 and 5) groups. Kappa statistics was used to evaluate the intra-and inter-examiner agreements and logistic regression analysis was used to explore the responsible factors that affect dental arch relationship. The mean GOSLON score was 3.15±0.9. Total 72 subjects (68% of all subjects) were categorized into favourable group (category rating 1, 2 and 3) using GOSLON Yardstick. Intra-and inter-examiner agreements were good to very good. Palatoplasty and cheiloplasty seemed to be correlated with favourable dental arch relationship using crude regression analysis but no significant associations were found. This multivariate study shows no significant association between various congenital and postnatal treatment factors and dental arch relationship.

Incidence of Egyptian Live Births of Cleft Lip and/or Palate in Cairo, Luxor, Aswan and New Valley Governorates: A Survey Study in 237,783 Children

“…Luxor governorates while the right sided was dominant in Aswan governorate. Similar findings also reported in Tanzania population [34], Madagascar population [35] and Malaysian population [36][37][38].…”

Clinical Investigation of Congenital Factor Affecting Craniofacial Morphology of Unilateral Cleft Lip and Palate in Japanese Patients

“…However, significantly lesser mandibular length (Go-Pog, p = 0.044) compared to presence of lateral incisor in the affected side of UCLP children was found. Foregoing studies also found no significant differences [5,[7][8][9][10][11][12][13][14][15]. UCLP children with positive family history of cleft had significantly lesser mandibular growth (SNB, p = 0.040) and posterior facial height (p = 0.033) and greater mandibular growth in relation to the facial plane (NA-Pog, p = 0.039).…”

“…Despite of being one of the most common orofacial birth defects, even a single study has not been conducted on any population to assess the CM outcome in relation to congenital factors that are under practice. That led us to the comparison of established outcome with the surveys of treatment outcome based on dental arch relationship [5,[7][8][9][10][11][12][13][14][15]27] and postnatal treatment factors [4] in other geographical locations. In our previous study, we assessed the postnatal treatment factors affecting CM in Japanese UCLP subjects [4].…”

“…Several studies and considerations on the impact of the primary operation, such as the type of cheiloplasty [6][7][8][9][10][11][12][13][14][15] and the type of palatoplasty [6][7][8][9][10][11][12][13][14][15][16][17] have been reported. The effect of preoperative orthopaedic plate was used or not have been reported too [5,7,16,18,19].…”

“…Many reports have been assessed the multiple congenital and postnatal factors that affect treatment outcome based of dental arch relationship of patients with UCLP [6][7][8][9][10][11][12][13][14][15]. As well as, several researches have been published about CM in patients with clefts [4,20,21], however, we know of no clinical research with large enough samples to take account of all congenital factors.…”