Treatment of Tattoos With a Picosecond Alexandrite Laser

Saedi, Nazanin; Metelitsa, Andrei I.; Petrell, Kathleen; Arndt, Kenneth A.; Dover, Jeffrey S.

doi:10.1001/archdermatol.2012.2894

Cited by 128 publications

(107 citation statements)

References 10 publications

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“…[10][11][12][13][14][15] In the present study, we also found that asphalt-and sand-embedded tattoos caused by abrasions from a fall or motor-vehicle accident and a graphite-embedded, pencil point puncture tattoo were effectively and safely cleared after 1-3 sessions of 1,064-nm, picosecond-domain Nd:YAG laser treatment. We suggest that the explosive but selective delivery of photoacoustic waves could have contributed to the rapid clinical improvement in the traumatic tattoos from various foreign bodies.…”

supporting

confidence: 77%

“…9 Furthermore, successive in vivo and in vitro experiments have found picosecond-domain lasers to be more advantageous in breaking down tattoo pigments of various colors and constituents than nanosecond-domain lasers. [10][11][12][13][14][15] In the present case series study, we analyzed the clinical efficacy and safety of a picosecond-domain Nd:YAG laser in the treatment of traumatic tattoos of various causes.…”

Section: Introductionmentioning

confidence: 99%

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Efficacy and Safety of Picosecond-Domain neodymium-Doped Yttrium Aluminum Garnet Laser Treatment on Various causes of Traumatic Tattoos

Goo¹,

Cho

2016

Medical Lasers

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supporting

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of Picosecond-Domain neodymium-Doped Yttrium Aluminum Garnet Laser Treatment on Various causes of Traumatic Tattoos

Goo¹,

Cho

2016

Medical Lasers

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“…The logic is that ns pulse duration might be too long for effective photothermolysis of small tattoo particles having thermal relaxation time (TRT) in ps ranges. These ps pulse lasers have shown better performance than ns lasers in either tattoo clearance per treatment session or the pain level in both preclinical studies [6] and clinical studies [7,8]. Currently tattoo laser treatments are usually performed in multiple sessions with several weeks apart [9].…”

Section: Introductionmentioning

confidence: 99%

Visualization of laser tattoo removal treatment effects in a mouse model by two-photon microscopy

Jang

Yoon

Kim

et al. 2017

Biomed. Opt. Express

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Abstract:Laser tattoo removal is an effective method of eliminating tattoo particles in the skin. However, laser treatment cannot always remove the unwanted tattoo completely, and there are risks of either temporary or permanent side effects. Studies using preclinical animal models could provide detailed information on the effects of laser treatment in the skin, and might help to minimize side effects in clinical practices. In this study, two-photon microscopy (TPM) was used to visualize the laser treatment effects on tattoo particles in both phantom specimens and in vivo mouse models. Fluorescent tattoo ink was used for particle visualization by TPM, and nanosecond (ns) and picosecond (ps) lasers at 532 nm were used for treatment. In phantom specimens, TPM characterized the fragmentation of individual tattoo particles by tracking them before and after the laser treatment. These changes were confirmed by field emission scanning electron microscopy (FE-SEM). TPM was used to measure the treatment efficiency of the two lasers at different laser fluences. In the mouse model, TPM visualized clusters of tattoo particles in the skin and detected their fragmentation after the laser treatment. Longitudinal TPM imaging observed the migration of cells containing tattoo particles after the laser treatment. These results show that TPM may be useful for the assessment of laser tattoo removal treatment in preclinical studies.

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“…They may lead to fewer adverse effects because they confine energy to their target, and lower fluences are required. [79][80][81] Fractionated picosecond handpieces have been developed for resurfacing and rejuvenation, including the 755-nm picosecond alexandrite laser PicoSure (Cynosure, Westford, MA), which contains a diffractive lens array (DLA) and the dual-wavelength 532/1064-nm holographic fractionated picosecond laser, PicoWay Resolve (Syneron Candela, Irvine, CA). The PicoSure with DLA received US Food and Drug Administration (FDA) approval in 2014 to treat acne scarring and rhytides, 81 while the PicoWay received FDA approval in 2014 to treat all tattoo colors.…”

Section: Picosecond Lasersmentioning

confidence: 99%

Advances in fractional technology for skin rejuvenation, skin tightening, drug delivery, and treating scars and skin defects

2017

Self Cite

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I n recent decades, there has been a revolution in energy-based treatment options for skin scarring, rejuvenation, and tightening. One of the most promising developments has been the introduction of fractional photothermolysis, developed by Anderson and Manstein in 2004. Fractionated systems deliver laser energy in a grid-like pattern, creating microscopic columns of ablative and/or coagulative damage termed microthermal zones (MTZs), which stimulate collagen remodeling.1 The incorporation of fractional photothermolysis into energy-based devices has allowed less destruction to surrounding tissue, leading to desired results with the minimization of unwanted side effects, leading to both ablative and nonablative laser devices becoming desirable treatment options for cutaneous scarring and rejuvenation. Given their impressive results, newer fractional laser treatment options, including picosecond lasers, quality-switched (QS) lasers, and combined ablative and nonablative lasers, are being investigated for the treatment of these common skin conditions.The following review addresses the current and emerging topics on fractional laser treatment of skin scarring and rejuvenation based on the device type, including ablative, nonablative, QS, picosecond, and hybrid fractional lasers (HFLs). Additionally, newer energy-based fractional devices, such as radiofrequency (RF) with and without microneedling and the use of fractionated technology for drug delivery, are discussed in the context of these common skin conditions. Fractionated lasersTreatment options for cutaneous scars and skin rejuvenation have evolved significantly since the rise in popularity of ablative lasers in the 1990s. Newer treatment options, including ablative fractional lasers (AFL) and nonablative fractional lasers (NAFL), have garnered favor, given the milder side effect profile in comparison with traditional fully ablative lasers. Ablative fractional lasersAcne scarring AFLs were developed in an attempt to achieve the efficacy of traditional ablative lasers with the milder side effect profile of fractional technology. Although a single treatment produces less dramatic, albeit noticeable, results than traditional fully ablative lasers can, multiple treatments result in greater clinical improvement.2 Currently, there are 3 types of AFLs available for scar treatment: the 10600-nm carbon dioxide (CO2), the 2940-nm erbium:yttrium aluminum garnet (Er:YAG), and the 2740-nm yttrium scandium gallium garnet (YSGG) lasers. AFL is associated with the increased risk of both protracted erythema and postinflammatory hyperpigmentation (PIH) in darker skin types, which has led many clinicians to prefer a longer series of NAFL treatments over AFL treatments to achieve similar results with a lower risk of side effects.Multiple studies support the efficacy of the fractional CO2 laser in acne scars. The overwhelming majority of these studies investigate the utility of these lasers in atrophic facial scars. While NAFLs typically require multiple sessions to achieve modest ...

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Treatment of Tattoos With a Picosecond Alexandrite Laser

Cited by 128 publications

References 10 publications

Efficacy and Safety of Picosecond-Domain neodymium-Doped Yttrium Aluminum Garnet Laser Treatment on Various causes of Traumatic Tattoos

Efficacy and Safety of Picosecond-Domain neodymium-Doped Yttrium Aluminum Garnet Laser Treatment on Various causes of Traumatic Tattoos

Visualization of laser tattoo removal treatment effects in a mouse model by two-photon microscopy

Advances in fractional technology for skin rejuvenation, skin tightening, drug delivery, and treating scars and skin defects

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