Treatment of seborrheic keratosis in bilateral external auditory canal using fiber CO2 laser

Cevizci, Raşit; Bezgin, Selin Üstün; Altın, Gökhan; Oran, Gülbin; Bayazıt, Yıldırım A.

doi:10.5606/kbbihtisas.2016.04810

Cited by 8 publications

(9 citation statements)

References 8 publications

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“…The CO 2 laser is an effective alternative option but with a slightly higher risk of scarring and pigmentary changes 51, 52 . Small case series have used intense pulsed light 53 , pulsed-dye laser 54 , Nd:YAG (neodymium-doped yttrium aluminum garnet) laser 55 , or the 755-nm alexandrite picosecond laser 56 for SK removal.…”

Section: Treatmentmentioning

confidence: 99%

Recent advances in managing and understanding seborrheic keratosis

Wollina

2019

F1000Res

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Seborrheic keratosis (SK) is a common benign epidermal tumor with predominance in adult patients. Whereas common SKs are more frequent in Caucasians, dermatosis papulosa nigra is more prevalent in patients with a Fitzpatrick skin type of at least 3. There seems to be a link between extrinsic skin aging and the occurrence of SK. Mutations of fibroblast growth factor receptor 3 and other signaling molecules are a frequent finding in SK lesions. However, this does not translate into any malignant potential. Viral infections are particularly common in genital lesions, although their pathogenetic relevance for SK is questionable. Different histologic and clinical subtypes have been identified. The great variability of SKs raises some difficulties in diagnosis. Dermoscopy is the preferred non-invasive diagnostic method, in particular to differentiate pigmented SKs from other pigment tumors, including cutaneous melanoma. Eruptive SKs can be a paraneoplastic condition known as the Leser–Trélat sign. New targeted cancer treatments can cause a pseudo-Leser–Trélat sign. The treatment in practice is mainly minor surgery, including cryosurgery, shave excisions, and laser-assisted removal. The medical approaches have only limited effects. Recently, two formulations for topical therapy have been evaluated: a product with 40% hydrogen peroxide (HP40) and an aqueous nitric–zinc complex. Based on clinical trials, HP40 seems to be a promising alternative to surgery, in particular for facial lesions.

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Section: Treatmentmentioning

confidence: 99%

Recent advances in managing and understanding seborrheic keratosis

Wollina

2019

F1000Res

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“…Small case series have reported the use of intense pulsed light, pulsed-dye laser, Nd:YAG (neodymium-doped yttrium aluminum garnet) laser, or the 755-nm alexandrite picosecond laser. [41][42][43][44] None of these studies was specifically designed for elderly patients, head-to-head comparison of the various laser treatments are missing.…”

Section: Managementmentioning

confidence: 99%

Differential Diagnosis and Management on Seborrheic Keratosis in Elderly Patients

Moscarella¹,

Brancaccio²,

Briatico³

et al. 2021

CCID

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Seborrheic keratoses are exceedingly common in the elderly and usually are easy to diagnose and do not require treatment. However, given their great variety of clinical presentation, they may give rise to false-positive cases, meaning that they may at times mimic melanoma, squamous cell carcinoma and basal cell carcinoma. On the other hand, melanoma may mimic seborrheic keratosis, leading to incorrect patient management. With this review, we would like to summarize the current knowledge about epidemiology, clinical, dermoscopic and reflectance confocal microscopy imaging of this common entity, and we also summarize the currently available treatment options.

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“…In several case series of DPN patients, the use of CO 2 laser treatment completely removed SK lesions without scar formation or significant discomfort [164][165][166]. CO 2 laser was also successfully used in 2 cases of irritated SK, with no evidence of recurrence at 6 and 12 months [167,168]. Additionally, a comparative study of erbium:YAG (Er:YAG) laser and cryosurgery in 42 SK patients reported superior healing, less hyperpigmentation, and more erythema in laser-treated groups [169].…”

Section: Laser and Light-based Therapymentioning

confidence: 99%

Advances in the Etiology, Detection, and Clinical Management of Seborrheic Keratoses

Sun

Halpern

2021

Dermatology

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Seborrheic keratoses (SKs) are ubiquitous, generally benign skin tumors that exhibit high clinical variability. While age is a known risk factor, the precise roles of UV exposure and immune abnormalities are currently unclear. The underlying mechanisms of this benign disorder are paradoxically driven by oncogenic mutations and may have profound implications for our understanding of the malignant state. Advances in molecular pathogenesis suggest that inhibition of Akt and APP, as well as existing treatments for skin cancer, may have therapeutic potential in SK. Dermoscopic criteria have also become increasingly important to the accurate detection of SK, and other noninvasive diagnostic methods, such as reflectance confocal microscopy and optical coherence tomography, are rapidly developing. Given their ability to mimic malignant tumors, SK cases are often used to train artificial intelligence-based algorithms in the computerized detection of skin disease. These technologies are becoming increasingly accurate and have the potential to significantly augment clinical practice. Current treatment options for SK cause discomfort and can lead to adverse post-treatment effects, especially in skin of color. In light of the discontinuation of ESKATA in late 2019, promising alternatives, such as nitric-zinc and trichloroacetic acid topicals, should be further developed. There is also a need for larger, head-to-head trials of emerging laser therapies to ensure that future treatment standards address diverse patient needs.

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Treatment of seborrheic keratosis in bilateral external auditory canal using fiber CO2 laser

Cited by 8 publications

References 8 publications

Recent advances in managing and understanding seborrheic keratosis

Recent advances in managing and understanding seborrheic keratosis

Differential Diagnosis and Management on Seborrheic Keratosis in Elderly Patients

Advances in the Etiology, Detection, and Clinical Management of Seborrheic Keratoses

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