Alphabet knowledge is a hallmark of early literacy and facilitating its development has become a primary objective of pre-school instruction and intervention. However, little agreement exists about how to promote the development of alphabet knowledge effectively. A meta-analysis of the effects of instruction on alphabet outcomes demonstrated that instructional impacts differed by type of alphabet outcome examined and content of instruction provided. School-based instruction yielded larger effects than home-based instruction; small-group instruction yielded larger effects than individual tutoring programs. We found minimal evidence of transfer of alphabet instruction to early phonological, reading, or spelling skills. Implications for research and practice are discussed.In the field of early literacy, alphabet knowledge refers to children's familiarity with letter forms, names, and corresponding sounds, as measured by recognition, production, and writing tasks. Together, such alphabet knowledge represents an important component of emergent literacy (Whitehurst & Lonigan, 1998). Children's knowledge of letter names and sounds is the best predictor of their later reading and spelling abilities (Hammill, 2004;Scarborough, 1998;Schatschneider, Fletcher, Francis, Carlson, & Foorman, 2004). Letter name and letter sound knowledge predict subsequent literacy skills independently of other important predictors including phonological awareness and oral language (Burgess & Lonigan, 1998;McBride-Chang, 1999;Wagner, Torgesen, & Rashotte, 1994). Preschool and kindergarten students with poor knowledge of letter names and sounds are more likely to struggle with learning to read and be classified as having reading disabilities (Gallagher, Frith, & Snowling, 2000;O'Connor & Jenkins, 1999;Torppa, Poikkeus, Laakso, Eklund, & Lyytinen, 2006). These children tend to fall further behind their peers in reading acquisition, leading to gaps in spelling, reading fluency, vocabulary, and comprehension skills (Stanovich, 1986;Torgesen, 2002).For these reasons, alphabet knowledge has become an important learning goal for young children. The National Association for the Education of Young Children (NAEYC) recognizes development of the alphabetic principle as a goal for the preschool years and proficiency in letter discrimination, letter naming, and letter-sound correspondences are expected during the kindergarten year (NAEYC, 1998). Standards for Head Start (U.S. Department of Health and Human Services & Administration for Children and Families, 2003) require children to demonstrate awareness of letters as individual symbols and the Correspondence concerning the manuscript ought to be sent to Shayne B. Piasta, The Ohio State University, Preschool Language and Literacy Lab, 535B Arps Hall, 1945 North High Street, Columbus, OH 43210-1172, (piasta.1@osu.edu Despite these initiatives, relatively little is known about the impact of early instruction on the development of alphabet knowledge. This fact is especially troublesome as large numb...