Transurethral radiofrequency energy collagen micro‐remodeling for the treatment of female stress urinary incontinence

Abstract

Non-surgical, transurethral RF micro-remodeling is a safe treatment for women with SUI. In women with moderate to severe SUI, this novel therapy resulted in statistically significant improvement in quality of life of a magnitude associated with patient satisfaction with the treatment. Women who underwent RF micro-remodeling demonstrated a statistically significant elevation in mean LPP at 12 months.

Nonsurgical transurethral collagen denaturation for stress urinary incontinence in women: 18‐month results from a prospective long‐term study

“…This interim analysis supports previously reported studies 4,6,7,14 demonstrating the efficacy and safety of transurethral collagen denaturation as a nonsurgical treatment option for women with SUI. This minimally invasive procedure can be performed under local anesthesia in a physician's office and requires negligible recovery time, making it an attractive treatment option.…”

Radiofrequency for the treatment of stress urinary incontinence in women

“…In 2006, Appell et al [17] published a two-arm study with 110 women randomly assigned to the experimental group and 63 to the sham control group. All patients had SUI documented on physical examination, a history of SUI, urethral hypermobility, and a leak point pressure of more than 60 cm H 2 0.…”

“…Although the procedure does not produce complete relief of all incontinence symptoms, it does create patient satisfaction and objective evidence of improved urine retention. The recent publication of a randomized trial in which transurethral treatment was compared with sham is an important advance in this fi eld, as previous studies have not been able to distinguish treatment effects from placebo effects [17]. The fi nding that adverse effects did not differ between the treatment and sham groups is a testament to the safety of this procedure.…”

Randomized trials in robotic surgery: a practical impossibility?

“…It was not until May 2006, when the trend had all but faded from clinical use, that the first data from a randomized controlled trial were published. They showed no improvement in quality of life compared to a sham procedure [9].…”