Radiofrequency for the treatment of stress urinary incontinence in women

Dillon, Benjamin; Dmochowski, Roger R.

doi:10.1007/s11934-009-0058-z

Cited by 29 publications

(14 citation statements)

References 20 publications

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“…Given that RF's energy is not absorbed by melanin, this is a safe technology for all kinds of skin, benefiting from a solid evidence in terms of safety, efficacy, and patient satisfaction. Non-ablative RF has been recently explored as a non-invasive strategy allowing for vaginal canal tightening [21].…”

Section: Clinical Reasonsmentioning

confidence: 99%

Vaginal hyperlaxity syndrome: a new concept and challenge

Palacios

2017

Gynecological Endocrinology

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Section: Clinical Reasonsmentioning

confidence: 99%

Vaginal hyperlaxity syndrome: a new concept and challenge

Palacios

2017

Gynecological Endocrinology

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“…Since RF energy is unabsorbed by melanin, the technology is safe for all skin types and has a proven clinical history in terms of safety, efficacy, and patient satisfaction. Although transurethral monopolar RF has been used to treat stress urinary incontinence with minimal risk of adverse events, nonablative RF has only recently been explored as a noninvasive strategy to achieve tightening of the vaginal canal (Dillon and Dmochowski, 2009). …”

Section: Rf-based Devices For Vaginal Rejuvenationmentioning

confidence: 99%

Vaginal rejuvenation using energy-based devices

Karcher

Sadick

2016

International Journal of Women's Dermatology

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Physiologic changes in a woman’s life, such as childbirth, weight fluctuations, and hormonal changes due to aging and menopause, may alter the laxity of the vaginal canal, damage the pelvic floor, and devitalize the mucosal tone of the vaginal wall. These events often lead to the development of genitourinary conditions such as stress urinary incontinence; vaginal atrophy; dryness; and physiologic distress affecting a woman’s quality of life, self-confidence, and sexuality. Various treatment modalities are currently available to manage these indications, varying from invasive vaginal surgery to more benign treatments like topical vaginal hormonal gels or hormone-replacement therapy. A new trend gaining momentum is the advent of energy-based devices for vaginal rejuvenation that apply thermal or nonthermal energy to the various layers of the vaginal tissue, stimulating collagen regeneration contracture of elastin fibers, neovascularization, and improved vaginal lubrication. This review aims to present the available technologies offering vaginal rejuvenation and the scientific evidence that underlines their safety and efficacy for this indication.

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“…These RF applications appear to be best suited for surface or luminal organs, as illustrated by its use in the treatment of stress urinary incontinence. 14 …”

Section: Non-ablative Radiofrequency Tissue Remodeling: Current Applimentioning

confidence: 99%

“…Since its introduction in 2002 and FDA approval in 2005, several longer-term studies have demonstrated safety and efficacy using this procedure for treating urinary incontinence in women who cannot tolerate or do not desire surgical intervention 9,[13][14][15]. …”

mentioning

confidence: 99%

Non-ablative hyperthermic mesenchymal regeneration: a proposed mechanism of action based on the Vivev model

et al. 2011

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Novel non-ablative hyperthermic medical devices are currently being developed, in association with cryogen surface cooling, to rejuvenate tissues without collagen scarring. These devices have been designed to remodel skin, manage urinary stress incontinence, and more recently, treat vaginal laxity. In contrast to the thermal injury and reparative healing associated with higher energy ablation systems, these lower energy non-ablative systems are designed to subtly modify the collagen, stimulate the fibroblasts, and maintain a functional tissue architecture that subsequently promotes tissue rejuvenation and restoration. While these devices have primarily relied on clinical outcome questionnaires and satisfaction surveys to establish efficacy, a physiologic explanation for the induced tissue changes and tightening has not been well documented. Recent histology studies, using the Viveve ovine vaginal treatment model, have identified changes that propose both a mechanism of action and a tissue remodeling timeline for such non-ablative hyperthermic devices. The Viveve model results are consistent with subtle connective tissue changes leading to fibroblast stimulation and subsequent collagen replacement and augmentation. Unlike tissue ablation devices that cause thermal necrosis, these non-ablative devices renew the targeted tissue without dense collagenous scarring over a period of 3 or more months. The spectrum of histologic findings, as illustrated in the Viveve ovine vaginal model, further support the previously documented safety and efficacy profiles for low-dose non-ablative hyperthermic devices that rejuvenate and tighten submucosal tissues.

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Radiofrequency for the treatment of stress urinary incontinence in women

Cited by 29 publications

References 20 publications

Vaginal hyperlaxity syndrome: a new concept and challenge

Vaginal hyperlaxity syndrome: a new concept and challenge

Vaginal rejuvenation using energy-based devices

Non-ablative hyperthermic mesenchymal regeneration: a proposed mechanism of action based on the Vivev model

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