“…Recent research suggests that disruption of the human microbiome may play a crucial role in diabetes (Burcelin et al, 2009), skin diseases (Grice et al, 2008), obesity (Backhed et al, 2004;Ley et al, 2005Ley et al, , 2006Turnbaugh et al, 2006;Cani and Delzenne, 2009;Tsukumo et al, 2009;Turnbaugh and Gordon, 2009) and a range of 'immuno-pathologic' conditions including inflammatory bowel diseases (Moore and Moore, 1995;Powrie and Uhlig, 2004;Rakoff-Nahoum et al, 2004;RakoffNahoum and Medzhitov, 2006). Colorectal cancer (CRC) is a prevalent malignancy within the western countries and is the second leading cause of cancer death in the United States (Jemal et al, 2010).…”