Efficient aeration of liquid mixtures is essential in many biochemical and chemical processes. The power requirements needed to obtain three-phase gas-liquid-liquid systems containing air, mineral oil, and water as modeling mixture were analyzed. The influence of using various kinds of agitators consisting of two stirrers on a common shaft and different volume fractions of oil ranging from 0.111 to 0.429 were investigated experimentally. The studies were performed for three configurations of stirrers consisting of Smith disc, Rushton, or flat-blade turbines.