Transition metal complexes with thiosemicarbazide-based ligands. Part LVI: Nickel(II) complex with 1,3-diphenylpyrazole-4-carboxaldehyde thiosemicarbazone and unusually deformed coordination geometry

Leovac, Vukadin M.; Novaković, Slađana B.; Bogdanović, Goran A.; Szécsényi, Katalin Mészáros; Češljević, Valerija I.

doi:10.1016/j.poly.2007.04.012

Cited by 31 publications

(23 citation statements)

References 36 publications

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“…Some new appear bands in the range (755 -777cm −1 ) assigned to groups (C-S) vibrations. This is also confirmed by the appearance of bands in the range of 395 -417 cm −1 , this has been assigned to the ν(M-N) [28], and the appearance of bands in the range of 490 -505 cm −1 , this has been assigned to the ν(M-O). A strong band found at 902 cm −1 is due to the ν(N-N) group of the 1,1oxalylbis(4-phenyl-thiosemicarbazide.…”

Section: Infrared Spectra Of H 4 Oxtsc (I) and Its Metal Complexessupporting

confidence: 58%

Spectral, Thermal and Antibacterial Studies for Bivalent Metal Complexes of Oxalyl, Malonyl and Succinyl-bis-4-phenylthiosemicarbazide Ligands

Amin¹,

Elreedy²,

Alansi³

et al. 2016

OJIC

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The thermogravimetry (TG) and derivative thermogravimetry (DTG) have been used to study the thermal decomposition of some oxalyl (H 4 OxTSC), malonyl (H 4 MaTSC) and succinyl-bis-4-phenylthiosemicarbazide (H 4 SuTSC) ligands and their metal complexes using Horowitz-Metzger (HM) and Coats-Redfern methods. The kinetic thermodynamic parameters such as: E*, ΔH*, ΔS*and ΔG* are calculated from the DTG curves. The isolated complexes have the general composition [M 2 (L) (H 2 O) 6 ], where M=Cu(II), Zn(II), L=MaTSC and M=Co(II), Cu(II) or Sn(II) and L=Su TSC and [M 2 (L) (H 2 O) n ]·nH 2 O where M=Cu(II), Co(II) or Sn(II), L=OxTS or Ma TSC. The tested compounds show a good activity against four strains of bacteria Gram negative Escherichia coli, Pseudomonas aeruginosa species and gram-positive Bacillus cereus and Staphylococcus aureus.Keywords Metal (II) Complexes, Bis-Thiosemicarbazide, Thermogravimetric, Antibacterial Studies 1. Introduction Thiosemicarbazide and its derivatives have received considerable attention because of their pharamacological * Corresponding author.R. R. Amin et al. 90 properties [1]. Thiosemicarbazide complexes show a broad spectrum of anticancer activity [2] [3]. Also, thiosemicarbazide derivatives are of current interest with respect to their uses as analytical reagents for separations of metal(II) ions [4]-[7], analytical determination of metal ions [8] [9], and clinical analysis [10]. Most of these compounds have antifungal [11]-[12], antimicrobial [13] and antitumor activity [14]-[16], as well as radiopharmaceuticals applications [17]. Continuing our studies for the chemical and electrochemical synthesis of new metal complexes of ligands containing N, S and O atoms through the reaction of metal ions scarified from the anodic dissolution of metals [18] [19]. Our aim work in this paper to report novel complexes prepared from the reaction between bisthiosemicarbazi decompounds which have a good ability to form chelate complexes with transition metal [18]- [20]. We report here the thermal, spectral and biological evaluations of Co(II), Cu(II), Zn(II) and Sn(II) complexes for 1,1-oxalyl, malonyl and succinyl-bis-4-phenylthiosemicarbazide ligands. The modern spectroscopic investigations are used to elucidate the structure of the prepared materials. The thermal decomposition is also used to infer the structure of the metal complexes and to calculate the different thermodynamic activation parameters. Experimental The Organic Compounds1) Preparation of 1,1-Oxalylhydrazide: 1,1-oxalyldihydrazine was prepared by adding oxalyl chloride (7 gm, 0.05 mol) to alcoholic solution of hydrazine hydrate (5 gm, 0.1 mole). The reaction mixture was exothermic and left to cool with stirring. A white crystal precipitate was formed and washed with ethanol diethyl ether and left to dry.2) Preparation of 1,1-Oxalylbis (4-phenylthiosemicarbazide): It was prepared by adding phenylisothiocynate (2.8 gm, 0.02 mol) to an alcoholic solution of oxalic acid dihydrazide (1.18 gm, 0.01 mole). The reaction mixture was refluxed f...

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Section: Infrared Spectra Of H 4 Oxtsc (I) and Its Metal Complexessupporting

confidence: 58%

Spectral, Thermal and Antibacterial Studies for Bivalent Metal Complexes of Oxalyl, Malonyl and Succinyl-bis-4-phenylthiosemicarbazide Ligands

Amin¹,

Elreedy²,

Alansi³

et al. 2016

OJIC

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“…They have been evaluated over the last 50 years as antiviral, antibacterial, and anticancer therapeutics, and biological activities of them are a function of parent aldehyde or ketone moiety [2][3][4][5][6][7]. Thiosemicarbazone is an important group of multidentate ligands and usually coordinates with the metal through the imine nitrogen and sulfur atom [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] (Scheme 1).…”

Section: Introductionmentioning

confidence: 99%

Synthesis, spectroscopic characterization, crystal structures, and theoretical studies of (E)-2-(2,4-dimethoxybenzylidene)thiosemicarbazone and (E)-2-(2,5-dimethoxybenzylidene)thiosemicarbazone

et al. 2010

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Two thiosemicarbazones, (E)-2-(2,4-dimethoxybenzylidene)thiosemicarbazone (24-MBTSC (1)) and (E)-2-(2,5-dimethoxybenzylidene)thiosemicarbazone (25-MBTSC (2)), derived from 2,4-dimethoxybenzaldehyde and 2,5-dimethoxybenzaldehyde, respectively, with thiosemicarbazide have been synthesized and their structures were characterized by elemental analyses, FT-IR, 1 H NMR spectroscopy, and X-ray single-crystal diffraction analysis. Molecular orbital calculations have been carried out for 1 and 2 by using an ab initio method (HF) and also density functional method (B3LYP) at 6-31G basis set. Compound 1 crystallizes in the monoclinic system, space group P2 1 /c, with a = 8.1342(5) Å , b = 18.1406(10) Å , c = 8.2847(6) Å , b = 109.7258(17)°, V = 1150.75(12) Å 3 , and Z = 4, whereas compound 2 crystallizes in the orthorhombic system, space group Pbca, with a = 11.0868(6) Å , b = 13.1332(6) Å , c = 15.9006(8) Å , V = 2315.2(2) Å 3 , and Z = 8. The compounds 1 and 2 displays a trans-configuration about the C=N double bond.

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“…Most of these compounds have antifungal [7], antimicrobial [8], antitumor [9], biological activity [10,11] as well as hypoglycemic effects [12][13][14]. In addition, thiosemicarbazide derivatives have ability to form chelate complexes with transition metal ions [15][16][17][18][19][20]. Continuing our studies for the electrochemical synthesis of new metal complexes of ligands containing N, S and O atoms through the reaction of metal ions scarified from the anodic dissolution of metals [16,21,22].…”

Section: Introductionmentioning

confidence: 99%

Kinetic parameters and thermal decomposition for Novel 1,1-Malonyl-bis(4-p-Chlorophenylthiosemicarbazide) and Cu(II), Co(II), Zn(II) and Sn(II) complexes(H<sub>4</sub>pClMaTS) synthesized by electrochemical method

Amin¹,

Yamany²,

Abo-Aly³

et al. 2011

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HNMR, mass), thermal, and ESR studies. The Raman and infrared spectral studies suggests the tridentate behavior of the ligand from each tail. Since the ligand has two thiosemicarbazide groups, it may acts in an SNO tridentate fashion from each side with one of the two metal ions forming a polynuclear complex coordinating through both of the lone pair of electrons the enolic oxygen of the carbonyl group (C=O), the azomethine nitrogen (C=N) and the thioenol form of the thiocarbonyl group (C=S). The differential thermogravimetric analysis (DTG) curves were used to study the decomposition steps of the isolated complexes using Horowitz-Metzger (HM) and Coats-Redfern (CR) methods. The kinetic thermodynamic parameters such as: E*, ∆H*, ∆S*and ∆G* are calculated from the DTG curves.

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Transition metal complexes with thiosemicarbazide-based ligands. Part LVI: Nickel(II) complex with 1,3-diphenylpyrazole-4-carboxaldehyde thiosemicarbazone and unusually deformed coordination geometry

Cited by 31 publications

References 36 publications

Spectral, Thermal and Antibacterial Studies for Bivalent Metal Complexes of Oxalyl, Malonyl and Succinyl-bis-4-phenylthiosemicarbazide Ligands

Spectral, Thermal and Antibacterial Studies for Bivalent Metal Complexes of Oxalyl, Malonyl and Succinyl-bis-4-phenylthiosemicarbazide Ligands

Synthesis, spectroscopic characterization, crystal structures, and theoretical studies of (E)-2-(2,4-dimethoxybenzylidene)thiosemicarbazone and (E)-2-(2,5-dimethoxybenzylidene)thiosemicarbazone

Kinetic parameters and thermal decomposition for Novel 1,1-Malonyl-bis(4-p-Chlorophenylthiosemicarbazide) and Cu(II), Co(II), Zn(II) and Sn(II) complexes(H<sub>4</sub>pClMaTS) synthesized by electrochemical method

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Transition metal complexes with thiosemicarbazide-based ligands. Part LVI: Nickel(II) complex with 1,3-diphenylpyrazole-4-carboxaldehyde thiosemicarbazone and unusually deformed coordination geometry

Cited by 31 publications

References 36 publications

Spectral, Thermal and Antibacterial Studies for Bivalent Metal Complexes of Oxalyl, Malonyl and Succinyl-bis-4-phenylthiosemicarbazide Ligands

Spectral, Thermal and Antibacterial Studies for Bivalent Metal Complexes of Oxalyl, Malonyl and Succinyl-bis-4-phenylthiosemicarbazide Ligands

Synthesis, spectroscopic characterization, crystal structures, and theoretical studies of (E)-2-(2,4-dimethoxybenzylidene)thiosemicarbazone and (E)-2-(2,5-dimethoxybenzylidene)thiosemicarbazone

Kinetic parameters and thermal decomposition for Novel 1,1-Malonyl-bis(4-p-Chlorophenylthiosemicarbazide) and Cu(II), Co(II), Zn(II) and Sn(II) complexes(H&lt;sub&gt;4&lt;/sub&gt;pClMaTS) synthesized by electrochemical method

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Kinetic parameters and thermal decomposition for Novel 1,1-Malonyl-bis(4-p-Chlorophenylthiosemicarbazide) and Cu(II), Co(II), Zn(II) and Sn(II) complexes(H<sub>4</sub>pClMaTS) synthesized by electrochemical method