Transformation Products of Brominated Flame Retardants (BFRs)

Dirtu, Alin C.; Ionas, Alin C.; Malarvannan, Govindan

doi:10.1002/9781118339558.ch18

Cited by 3 publications

(2 citation statements)

References 107 publications

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“…Restrictions on the manufacture and use of DecaBDE have followed, and it was listed in 2017 under Annex A of the Stockholm Convention. A key consideration with respect to the listing of DecaBDE under the Stockholm Convention is its potential to form lower BDEs by various debromination processes 3 .…”

Section: Introductionmentioning

confidence: 99%

Legacy PBDEs and NBFRs in sediments of the tidal River Thames using liquid chromatography coupled to a high resolution accurate mass Orbitrap mass spectrometer

Ganci

Vane

Abdallah

et al. 2019

Science of The Total Environment

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Section: Introductionmentioning

confidence: 99%

Legacy PBDEs and NBFRs in sediments of the tidal River Thames using liquid chromatography coupled to a high resolution accurate mass Orbitrap mass spectrometer

Ganci

Vane

Abdallah

et al. 2019

Science of The Total Environment

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“…Thermal degradation of HBCDDs results in the formation of high‐molecular weight aromatic and polyaromatic brominated decomposition compounds (Dirtu et al., 2014). In the same way as polychlorinated dioxins and furans can be produced when organochlorine compounds are combusted, polybrominated dioxins and furans may be generated in low amounts when organobromine‐containing products are combusted (D'Silva et al., 2004; Jogsten et al., 2010; Piskorska‐Plisczynska and Maszewski, 2014; IPEN, 2019).…”

Section: Introductionmentioning

confidence: 99%

Update of the risk assessment of hexabromocyclododecanes (HBCDDs) in food

Schrenk

Bignami

Bodin³

et al. 2021

EFS2

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The European Commission asked EFSA to update its 2011 risk assessment on hexabromocyclododecanes ( HBCDD s) in food. HBCDD s, predominantly mixtures of the stereoisomers α‐, β‐ and γ‐ HBCDD , were widely used additive flame retardants. Concern has been raised because of the occurrence of HBCDD s in the environment, food and in humans. Main targets for toxicity are neurodevelopment, the liver, thyroid hormone homeostasis and the reproductive and immune systems. The CONTAM Panel concluded that the neurodevelopmental effects on behaviour in mice can be considered the critical effects. Based on effects on spontaneous behaviour in mice, the Panel identified a lowest observed adverse effect level ( LOAEL ) of 0.9 mg/kg body weight (bw) as the Reference Point, corresponding to a body burden of 0.75 mg/kg bw. The chronic intake that would lead to the same body burden in humans was calculated to be 2.35 μg/kg bw per day. The derivation of a health‐based guidance value ( HBGV ) was not considered appropriate. Instead, the margin of exposure ( MOE ) approach was applied to assess possible health concerns. Over 6,000 analytical results for HBCDD s in food were used to estimate the exposure across dietary surveys and age groups of the European population. The most important contributors to the chronic dietary LB exposure to HBCDD s were fish meat, eggs, livestock meat and poultry. The CONTAM Panel concluded that the resulting MOE values support the conclusion that current dietary exposure to HBCDD s across European countries does not raise a health concern. An exception is breastfed infants with high milk consumption, for which the lowest MOE values may raise a health concern.

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Analysis of Dioxin and Dioxin-Like Compounds

Reiner

2016

The Handbook of Environmental Chemistry

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Transformation Products of Brominated Flame Retardants (BFRs)

Cited by 3 publications

References 107 publications

Legacy PBDEs and NBFRs in sediments of the tidal River Thames using liquid chromatography coupled to a high resolution accurate mass Orbitrap mass spectrometer

Legacy PBDEs and NBFRs in sediments of the tidal River Thames using liquid chromatography coupled to a high resolution accurate mass Orbitrap mass spectrometer

Update of the risk assessment of hexabromocyclododecanes (HBCDDs) in food

Analysis of Dioxin and Dioxin-Like Compounds

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