Transcatheter closure of secundum atrial septal defects with the atrial septal defect occlusion system (ASDOS): initial experience in children.

Abstract

Objective-To report initial experiences with transcatheter occlusion of atrial septal defects using a new occlusion device.

Pediatric Therapeutic Cardiac Catheterization

“…For deployment, simultaneous venous and arterial access is necessary. The device has been used clinically, 109,110 and the results of the initial phase have been encouraging. 111 All of the ASD devices require transesophageal echocardiographic guidance for optimal placement.…”

A comparison of arterial versus venous-activated clotting time in patients with congenital heart disease undergoing cardiac catheterization

“…Practice standards for heparin dosing for occlusion devices and stents do not exist. For device closure of atrial septal defect, higher values of ACT in the range of 300-400 sec are recommended based on the surgical experience, but all is based on unpublished observation [7,8].…”

Amplatzer Device closure of Atrial Septal Defects and Patent Ductus Arteriosus: Initial Experience

“…However, the procedure has not yet achieved widespread clinical use and is still investigational. Previous devices include the clamshell septal occluders [3,4], Sideris prosthesis (buttoned device) [5][6][7], the atrial septal defect occlusion system (ASDOS) [8,9], the Das Angel Wing [10,11] and the Pavenik monodisc [12]. All these were bulky devices, requiring larger sheaths for introduction which make their application difficult in small children.…”

“…As an alternative to surgery, a variety of devices for transcatheter closure of ASDs have been developed over the past 25 years, but none has gained wide acceptance. Large delivery sheaths, cumbersome implantation techniques, inability to recapture, structural failure, dislodgement and embolization of the device are some of the limitations of previously prescribed techniques [2][3][4][5][6][7][8][9][10][11][12]. This study describes our experience with transcatheter closure of ASDs and PDAs using a new self expanding, self-centering and repositionable device, the Amplatzer.…”