A comparison of arterial versus venous-activated clotting time in patients with congenital heart disease undergoing cardiac catheterization

Anticoagulation and Pediatric Extracorporeal Membrane Oxygenation: Impact of Activated Clotting Time and Heparin Dose on Survival

“…Technical factors that may impact ACT accuracy include agitator and timers [15], lack of single sample precision [16], venous versus arterial blood [17], smaller sample volumes [4], temperature, and timing of ACT levels [18]. Many studies [9,19,20] support that different ACT analyzers, such as HemoTec, Hemochron, and Hemochron Jr, frequently produce different results.…”

Venous or arterial samples for activated clotting time measurements: a systematic review

“…In coronary angioplasty it is permissible to have ACT measurements between 300 and 400 seconds, despite the lack of a standardised guideline. 9…”

“…In coronary angioplasty it is permissible to have ACT measurements between 300 and 400 seconds, despite the lack of a standardised guideline. 9 Zeevi et al studied the variation in measurements between venous and arterial samples when heparin was delivered using the dual chambered Haemochron blood coagulation timing system. In order to measure ACT, 2 ml of blood were withdrawn from the venous and arterial lines and a total of 4 ml of blood disposed.…”

“…There was no significant difference between venous and arterial ACT values in this study. 9 Variability of ACT measurement has been reported in coronary angioplasty. Warner et al reported arterial ACT measurements were 70% higher than venous values.…”