Toxicology, Environmental Health, and the “One Health” Concept

Abstract

The One Health concept promotes collaboration among veterinarians, physicians, scientists, and other professions to promote human, animal, and ecosystem health. One Health illustrates the interconnectedness and interdependence of human, animal, and ecosystem health. This concept has traditionally focused on zoonoses that are infectious diseases, not on chemical-or poison-related illnesses in animals and their relationship to the detection and prevention of human illness. The purpose of this article is to describe key experiences of scientists in the Health Studies Branch within the National Center for Environmental of Health of the Centers for Disease Control and Prevention in which the study of animal illness facilitated a public health investigation into an outbreak of chemicalassociated human disease. The experiences highlight how utilizing the One Health approach may improve chemicalassociated outbreak investigations and facilitate appropriate intervention strategies. An appropriate One Health approach in toxicology and environmental health in outbreak settings should include consideration of the common environments and food sources shared by humans and animals and consideration of the potential for contaminated animal products as food sources in human exposures.

Toward Proof of Concept of a One Health Approach to Disease Prediction and Control

“…Evidence for feasibility of integration across all 3 sectors of human, animal, and environmental health, however, came from other studies, such as an article detailing how reports of animal illness facilitated investigations of human cases of disease caused by chemical hazards in the indoor environment ( 14 ). Likewise, a recent state-based effort found benefits of working across human, animal, and environmental health sectors for simultaneously tracking risk for rabies and white nose syndrome in bats ( 16 ), and an effort to track Campylobacter infection in poultry found that environmental temperature affected infection risk for broiler flocks and for humans.…”

Characterization of Animal Exposure Calls Captured by the National Poison Data System, 2000-2010

“…Since 2001, the Centers for Disease Control and Prevention has collaborated with AAPCC to use NPDS for national public health surveillance of chemical and poison exposures and illness. Surveillance efforts to date have focused primarily on human health threats but animal illness can serve as a sentinel event for human illness [20]. Surveillance methodologies can also be created for animal exposures and illness.…”

The highly incident causes of accidental poisoning in camels and sheep in Saudi Arabia and their economic impact

“…Poison in common is a dose-dependent potential hazard that adversely affects the standard physiological functions and may threaten the life of living beings (Descotes and Vial, 1994;zhu et al, 2017). The manner of livestock poisoning is frequently associated with the environment imposed by human (Balagangatharathilagar, et al, 2006;Lightfoot and Yeager, 2008;Buttke, 2011). Potential sources of xenobiotics that adversely affect animals include contaminated feed, water, air, and soil (Donner et al, 2010).…”