Toward Proof of Concept of a One Health Approach to Disease Prediction and Control

Abstract

A One Health approach considers the role of changing environments with regard to infectious and chronic disease risks affecting humans and nonhuman animals. Recent disease emergence events have lent support to a One Health approach. In 2010, the Stone Mountain Working Group on One Health Proof of Concept assembled and evaluated the evidence regarding proof of concept of the One Health approach to disease prediction and control. Aspects examined included the feasibility of integrating human, animal, and environmental health and whether such integration could improve disease prediction and control efforts. They found evidence to support each of these concepts but also identified the need for greater incorporation of environmental and ecosystem factors into disease assessments and interventions. The findings of the Working Group argue for larger controlled studies to evaluate the comparative effectiveness of the One Health approach.

Antimicrobial multiple resistance index, minimum inhibitory concentrations, and extended-spectrum beta-lactamase producers of Proteus mirabilis and Proteus vulgaris strains isolated from domestic animals with various clinical manifestations of infection

“…Based on our findings, the selection of first-line drugs for treatment should be based on local in vitro resistance patterns. Indeed, the responsible use of antimicrobials for domestic animals is an emergent precept of the "One Health" concept, to conserve these drugs for human therapy approaches (RABINOWITZ et al, 2013).…”

Taenia solium Taeniasis and Cysticercosis in Southeast Asia

“…3,14 In other words, an integrated One Health approach is necessary with political commitment and inter-sectoral collaboration at local, national, and international levels. 29,44,77 However, to date, high-quality evidence on the impact of community-based control strategies is largely lacking. A recent study searched all published literature and analyzed the effectiveness of community-based control strategies, employing either a single or a combination of multiple interventions that used pre-and post-intervention designs.…”

Organizational leadership perspectives in implementation of the One Health approach: A case of the Zoonotic Disease Unit and core One Health implementers in Kenya

“…Despite increasing global momentum of the OH approach, there are relatively few practical examples of long-term commitment to and progress in its implementation at national and grass-root levels [2,12]. Various authors have stated the need to generate more evidence to inform concrete policy shifts toward adoption of OH approach at these levels [2,13].…”

“…Various authors have stated the need to generate more evidence to inform concrete policy shifts toward adoption of OH approach at these levels [2,13]. Diverse factors such as awareness, leadership, technical capacities, and policies influence intersectoral collaboration [14][15][16].…”

“…In the recent years, emerging diseases with serious socioeconomic consequences have re-awakened the global community to the need for cross-sectoral collaboration in addressing health matters [1][2][3]. The Ebola outbreak in Western Africa, for instance, costed over USD 6 billion in direct expenses and at least USD 15 billion in indirect economic losses by March 2015 [4].…”