Toxic effects of two organophosphorus pesticides on fructose-1,6-diphosphate aldolase activity of liver, brain and gills of the freshwater fish Clarias batrachus

Tandon, R. S.; Dubey, Ajai

doi:10.1016/0143-1471(83)90049-1

Cited by 11 publications

(3 citation statements)

References 7 publications

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“…Any interference in enzyme activity lead to biochemical impairment, cellular dysfunction, metabolic and physiological activities of the fish. Abnormal behavioral patterns, exhibited by C. batrachus during the experiment indicated its efforts to ward off the situation and were identical to that reported in fishes subjected to different pesticides by Tandon and Dubey, 1983;Tripathi and Shukla, 1988;Lata et al, 2001 andChandra, 2008. Hyperphosphatemia has been noticed in fish after exposure to various toxicants (Gupta et al, 1975;Singh et al, 1996;Yogesh and Saxena, 1999;Singh and Saxena, 2001).…”

Section: Discussionsupporting

confidence: 63%

Impact of pesticide Rogor toxicity on serum phosphomonoesterase levels of freshwater catfish Clarias batrachus

Chandra¹

2013

JANS

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Abstract:The exposure of pesticide Rogor had significantly altered serum alkaline and acid phosphatase activities in freshwater catfish, Clarias batrachus at different concentrations and duration under static conditions. However, the intensity of activity of both the enzymes were interestingly different. The fish elicited marked behavioral changes with increasing concentrations and exposure duration. The rising trend in enzyme levels which mediate membrane transport mechanism and biosynthesis of macromolecules, have been correlated with the induction and leakage of respective enzymes from liver following membrane damage and necrosis due to pesticide toxicity.

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Section: Discussionsupporting

confidence: 63%

Impact of pesticide Rogor toxicity on serum phosphomonoesterase levels of freshwater catfish Clarias batrachus

Chandra¹

2013

JANS

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“…Many chemicals at relatively low dosages affect the metabolism of biota by altering normal enzyme activity (2,3,4,5,6,7,8,9).…”

mentioning

confidence: 99%

The effects of some pesticites on the activity of liver and erythrocyt enzymes (in vitro)

Çelik

Arslan

Yeğin

et al. 1996

Journal of Environmental Science and Health . Part A: Environme

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The effect of pomarsol (tetramethyltriurem disulphide), Benlate 1-(NButlycarbomoyl) 2-(Metoxycarboxamido)-bezimidazol, meothrin (α-cyanophenoxbenzyl 2.2.3.3.-tetramethyI cyclopropanecarbonylate), Imperator [α-cyano 3-phenoxybenzylcis, trans-3-(2.2-dichroinyl)-2.2-dimetil research on GOT, GPT (liver enzymes) and CA-I, CA-II (Human erythrocyt) BCA (Bovine erythrocyt). Among the chemicals meothrin, imperator, sumicidin were determined to have inhibitory effect, on bovine CA, human CA and GOT enzymes, but ineffective on GPT enzyme. The I 50 values of chemicals caused inhibition were determined by means of activity percentage [I]diagrams. The values were 3.2×10 -2 M, 3.5×10 -2 M, 2.7×10 -2 M for GOT respectively.

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“…Chandra (1988) opined that malathion may (50) lead to inhibition of cholinesterase at neuro effector sites in adrenal medulla, leading to hypersecretion of adrenalin which resulted in hypermetabolic conditions to meet stress condition. Tandon and Dubey (1983) reported increased aldolase activity, an important gluconeogenic enzyme to withstand the stress condition caused by pesticide malathion and dimicron in Clarias batrachus. Marked inhibition in AchE in different tissues of fish following exposure to higher concentration of sumithion has been reported by Koundiya and Ramamurthy (1978), Dubey (1980), Natrajan (1984), Thannipon et al (1995) and Sudheer Kumar et al (2006).…”

Section: Discussionmentioning

confidence: 99%

Toxic effect of malathion on acetylcholinesterase activity of liver, brain and gills of freshwater catfish Heteropneustes fossilis

Chandra¹

2008

ECJ

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The toxic effects of malathion were evident in the inhibition of acetylcholinesterase activity of liver, brain and gills of freshwater catfish Heteropneustes fossilis. Maximum inhibition of 77. 12% and 72.83% were recorded in brain and gills respectively after 72 hour of exposure to 4.80 mg/l pesticide. However, in liver highest inhibition of 67. 81% in enzyme level was noticed at 6.50 mg/l pesticide concentration after 24 hours of exposure, beyond which fish could not survive. Pesticide repressed the enzyme activity so intensely that it showed no sign of return to normalcy. The fish also elicited dissociated behaviour with increasing concentrations of pesticide toxicity.

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Toxic effects of two organophosphorus pesticides on fructose-1,6-diphosphate aldolase activity of liver, brain and gills of the freshwater fish Clarias batrachus

Cited by 11 publications

References 7 publications

Impact of pesticide Rogor toxicity on serum phosphomonoesterase levels of freshwater catfish Clarias batrachus

Impact of pesticide Rogor toxicity on serum phosphomonoesterase levels of freshwater catfish Clarias batrachus

The effects of some pesticites on the activity of liver and erythrocyt enzymes (in vitro)

Toxic effect of malathion on acetylcholinesterase activity of liver, brain and gills of freshwater catfish Heteropneustes fossilis

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